ATR Antibody (1E9) - Azide and BSA Free | Novus Biologicals H00000545-M03 product information

product summary

company name :

Novus Biologicals

other brands :

IMGENEX

product type :

antibody

product name :

ATR Antibody (1E9) - Azide and BSA Free

catalog :

H00000545-M03

quantity :

0.1 mg

price :

549 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1.00E+09

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Novus Biologicals product webpage

citations: 5

Reference
Savva C, De Souza K, Ali R, Rakha E, Green A, Madhusudan S. Clinicopathological significance of ataxia telangiectasia-mutated (ATM) kinase and ataxia telangiectasia-mutated and Rad3-related (ATR) kinase in MYC overexpressed breast cancers. Breast Cancer Res Treat. 2019;175:105-115 pubmed publisher
Al Subhi N, Ali R, Abdel Fatah T, Moseley P, Chan S, Green A, et al. Targeting ataxia telangiectasia-mutated- and Rad3-related kinase (ATR) in PTEN-deficient breast cancers for personalized therapy. Breast Cancer Res Treat. 2018;169:277-286 pubmed publisher
Abdel Fatah T, Middleton F, Arora A, Agarwal D, Chen T, Moseley P, et al. Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer. Mol Oncol. 2015;9:569-85 pubmed publisher
Abdel Fatah T, Perry C, Arora A, Thompson N, Doherty R, Moseley P, et al. Is there a role for base excision repair in estrogen/estrogen receptor-driven breast cancers?. Antioxid Redox Signal. 2014;21:2262-8 pubmed publisher
Sultana R, Abdel Fatah T, Perry C, Moseley P, Albarakti N, Mohan V, et al. Ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase inhibition is synthetically lethal in XRCC1 deficient ovarian cancer cells. PLoS ONE. 2013;8:e57098 pubmed publisher

product information

master code :

H00000545-M03

SKU :

H00000545-M03

product name :

ATR Antibody (1E9) - Azide and BSA Free

unit size :

0.1 mg

description :

The ATR Antibody (1E9) - Azide and BSA Free from Novus is a mouse monoclonal antibody to ATR. This antibody reacts with hamster,human,rat. The ATR Antibody (1E9) - Azide and BSA Free has been validated for the following applications: IF/IHC,Western Blot,Immunohistochemistry-Paraffin,ELISA,Immunohistochemistry.

target :

ATR

category :

Primary Antibodies

buffer :

In 1x PBS, pH 7.4

clonality :

Monoclonal

clone :

1.00E+09

conjugate :

Unconjugated

host :

Mouse

immunogen :

DQREPLMSVLKTFLHDPLVEWSKPVKGHSKAPLNETGEV
VNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHY
LIQEATDENLLCQMYLGWTPYM
ATR (NP_001175, 2545 a.a. ~ 2644 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

isotype :

IgG1 Kappa

purity :

IgG purified

species :

Hamster,Human,Rat

specificity :

ATR - ataxia telangiectasia and Rad3 related (1E9)

gene symbol :

ATR

accessionNumbers :

NP_001175

applications :

IF/IHC,Western Blot,Immunohistochemistry-Paraffin,ELISA,Immunohistochemistry

USD :

549 USD

alt names :

ataxia telangiectasia and Rad3 related, Ataxia telangiectasia and Rad3-related protein, EC 2.7.11.1, FRAP-related protein 1, FRP1FRAP-related protein-1, MEC1, protein kinase ATR, Rad3 related protein, SCKL1, SCKLMEC1, mitosis entry checkpoint 1, homolog, serine/threonine-protein kinase ATR

storage :

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

more info or order :

Novus Biologicals product webpage