product summary
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company name :
Novus Biologicals
other brands :
IMGENEX
product type :
antibody
product name :
ATF4 Antibody (2B3) - Azide and BSA Free
catalog :
H00000468-M01
quantity :
0.1 mg
price :
529 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2B3
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry
more info or order :
citations: 8
Reference
Zhou B, Lu Q, Liu J, Fan L, Wang Y, Wei W, et al. Melatonin Increases the Sensitivity of Hepatocellular Carcinoma to Sorafenib through the PERK-ATF4-Beclin1 Pathway. Int J Biol Sci. 2019;15:1905-1920 pubmed publisher
Di Benedetto A, Posa F, De Maria S, Ravagnan G, Ballini A, Porro C, et al. Polydatin, Natural Precursor of Resveratrol, Promotes Osteogenic Differentiation of Mesenchymal Stem Cells. Int J Med Sci. 2018;15:944-952 pubmed publisher
Wang L, Wang X, Zhang S, Qu G, Liu S. A protective role of heme-regulated eIF2? kinase in cadmium-induced toxicity in erythroid cells. Food Chem Toxicol. 2013;62:880-91 pubmed publisher
Ghemrawi R, Pooya S, Lorentz S, Gauchotte G, Arnold C, Gueant J, et al. Decreased vitamin B12 availability induces ER stress through impaired SIRT1-deacetylation of HSF1. Cell Death Dis. 2013;4:e553 pubmed publisher
Wang X, Guo B, Li Q, Peng J, Yang Z, Wang A, et al. miR-214 targets ATF4 to inhibit bone formation. Nat Med. 2013;19:93-100 pubmed publisher
Suragani R, Zachariah R, Velazquez J, Liu S, Sun C, Townes T, et al. Heme-regulated eIF2? kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis. Blood. 2012;119:5276-84 pubmed publisher
Cole B, Kuhn N, Green Mitchell S, Leone K, Raab R, Nadler J, et al. 12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response. Am J Physiol Endocrinol Metab. 2012;302:E654-65 pubmed publisher
Meister S, Frey B, Lang V, Gaipl U, Schett G, Schlötzer Schrehardt U, et al. Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells. Neoplasia. 2010;12:550-61 pubmed
product information
master code :
H00000468-M01
SKU :
H00000468-M01
product name :
ATF4 Antibody (2B3) - Azide and BSA Free
unit size :
0.1 mg
description :
The ATF4 Antibody (2B3) - Azide and BSA Free from Novus is a mouse monoclonal antibody to ATF4. This antibody reacts with human,mouse. The ATF4 Antibody (2B3) - Azide and BSA Free has been validated for the following applications: Western Blot,ELISA,Immunocytochemistry/ Immunofluorescence.
target :
ATF4
category :
Primary Antibodies
buffer :
In 1x PBS, pH 7.4
clonality :
Monoclonal
clone :
2B3
conjugate :
Unconjugated
host :
Mouse
immunogen :
SSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIK
EEDTPSDNDSGICMSPESYLGSPQHSPSTRGSPNRSLPS
PGVLCGSARPKPYDPPGEKMVA
ATF4 (NP_001666.2, 171 a.a. ~ 270 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
isotype :
IgG1 Kappa
purity :
IgG purified
species :
Human,Mouse
specificity :
ATF4 - activating transcription factor 4 (tax-responsive enhancer element B67)
gene symbol :
ATF4
accessionNumbers :
P18848
applications :
Western Blot,ELISA,Immunocytochemistry/ Immunofluorescence
USD :
529 USD
alt names :
Activating transcription factor 4, activating transcription factor 4 (tax-responsive enhancer element B67), cAMP-dependent transcription factor ATF-4, cAMP-responsive element-binding protein 2, CREB-2DNA-binding protein TAXREB67, cyclic AMP-dependent transcription factor ATF-4, Cyclic AMP-responsive element-binding protein 2, TaxREB67, TAXREB67CREB2cAMP response element-binding protein 2, Tax-responsive enhancer element-binding protein 67, TXREB
storage :
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
more info or order :
company information
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
novus@novusbio.com
https://www.novusbio.com
3037301950
headquarters: USA
Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.