| Reference |
|---|
Howard S, Ceppi I, Anand R, Geiger R, Cejka P. The internal region of CtIP negatively regulates DNA end resection. Nucleic Acids Res. 2020;48:5485-5498 pubmed publisher |
Ragamin A, Yigit G, Bousset K, Beleggia F, Verheijen F, de Wit M, et al. Human RAD50 deficiency: Confirmation of a distinctive phenotype. Am J Med Genet A. 2020;182:1378-1386 pubmed publisher |
Qi F, Meng Q, Hayashi I, Kobayashi J. FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses. J Radiat Res. 2020;61:368-375 pubmed publisher |
Mooser C, Symeonidou I, Leimbacher P, Ribeiro A, Shorrocks A, Jungmichel S, et al. Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation. Nat Commun. 2020;11:123 pubmed publisher |
Völkening L, Vatselia A, Asgedom G, Bastians H, Lavin M, Schindler D, et al. RAD50 regulates mitotic progression independent of DNA repair functions. FASEB J. 2020;34:2812-2820 pubmed publisher |
Yoshimura Y. Increased error-free DNA repair gene expression through reprogramming in human iPS cells. Regen Ther. 2019;11:101-105 pubmed publisher |
Korsholm L, Gál Z, Lin L, Quevedo O, Ahmad D, Dulina E, et al. Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair. Nucleic Acids Res. 2019;47:8019-8035 pubmed publisher |
Leimbacher P, Jones S, Shorrocks A, De Marco Zompit M, Day M, Blaauwendraad J, et al. MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis. Mol Cell. 2019;74:571-583.e8 pubmed publisher |
Qin B, Yu J, Nowsheen S, Wang M, Tu X, Liu T, et al. UFL1 promotes histone H4 ufmylation and ATM activation. Nat Commun. 2019;10:1242 pubmed publisher |
Erickson K, Garcea R. Viral replication centers and the DNA damage response in JC virus-infected cells. Virology. 2019;528:198-206 pubmed publisher |
Anand R, Jasrotia A, Bundschuh D, Howard S, Ranjha L, Stucki M, et al. NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation. EMBO J. 2019;38: pubmed publisher |
Suh K, Ryu H, Lee K, Kim H, Min A, Kim T, et al. Prognostic effects of abnormal DNA damage response protein expression in breast cancer. Breast Cancer Res Treat. 2019;175:117-127 pubmed publisher |
Lamarche B, Orazio N, Goben B, Meisenhelder J, You Z, Weitzman M, et al. Repair of protein-linked DNA double strand breaks: Using the adenovirus genome as a model substrate in cell-based assays. DNA Repair (Amst). 2019;74:80-90 pubmed publisher |
Gao Y, Kardos J, Yang Y, Tamir T, Mutter Rottmayer E, Weissman B, et al. The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells. Sci Rep. 2018;8:15304 pubmed publisher |
Gustafsson N, Färnegårdh K, Bonagas N, Ninou A, Groth P, Wiita E, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018;9:3872 pubmed publisher |
Qian M, Liu Z, Peng L, Tang X, Meng F, Ao Y, et al. Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria. elife. 2018;7: pubmed publisher |
Pancholi N, Weitzman M. Serotype-specific restriction of wild-type adenoviruses by the cellular Mre11-Rad50-Nbs1 complex. Virology. 2018;518:221-231 pubmed publisher |
Moyal L, Goldfeiz N, Gorovitz B, Rephaeli A, Tal E, Tarasenko N, et al. AN-7, a butyric acid prodrug, sensitizes cutaneous T-cell lymphoma cell lines to doxorubicin via inhibition of DNA double strand breaks repair. Invest New Drugs. 2018;36:1-9 pubmed publisher |
Ward T, McHugh P, Durant S. Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes. PLoS ONE. 2017;12:e0179278 pubmed publisher |
Burke R, Marcus J, Orth J. Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells. Oncotarget. 2017;8:39460-39475 pubmed publisher |
Mariggiò G, Koch S, Zhang G, Weidner Glunde M, Rückert J, Kati S, et al. Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency. PLoS Pathog. 2017;13:e1006335 pubmed publisher |
Zhou H, Kawamura K, Yanagihara H, Kobayashi J, Zhang Akiyama Q. NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein. J Radiat Res. 2017;58:487-494 pubmed publisher |
Smith E, Gole B, Willis N, Soria R, Starnes L, Krumpelbeck E, et al. DEK is required for homologous recombination repair of DNA breaks. Sci Rep. 2017;7:44662 pubmed publisher |
Campos León K, Wijendra K, Siddiqa A, Pentland I, Feeney K, Knapman A, et al. Association of Human Papillomavirus 16 E2 with Rad50-Interacting Protein 1 Enhances Viral DNA Replication. J Virol. 2017;91: pubmed publisher |
Lou D, Kim E, Meyerson N, Pancholi N, Mohni K, Enard D, et al. An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates. Cell Host Microbe. 2016;20:178-88 pubmed publisher |
Xu Z, Song Z, Li G, Tu H, Liu W, Liu Y, et al. H2B ubiquitination regulates meiotic recombination by promoting chromatin relaxation. Nucleic Acids Res. 2016;44:9681-9697 pubmed |
Mlody B, Adjaye J. Generation of iPSC lines from a Nijmegen Breakage Syndrome patient. Stem Cell Res. 2015;15:629-32 pubmed publisher |
Francia S, Cabrini M, Matti V, Oldani A, d Adda di Fagagna F. DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors. J Cell Sci. 2016;129:1468-76 pubmed publisher |
Wijnhoven P, Konietzny R, Blackford A, Travers J, Kessler B, Nishi R, et al. USP4 Auto-Deubiquitylation Promotes Homologous Recombination. Mol Cell. 2015;60:362-73 pubmed publisher |
Xing M, Wang X, Palmai Pallag T, Shen H, Helleday T, Hickson I, et al. Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. Oncotarget. 2015;6:37638-46 pubmed publisher |
Mano M, Ippodrino R, Zentilin L, Zacchigna S, Giacca M. Genome-wide RNAi screening identifies host restriction factors critical for in vivo AAV transduction. Proc Natl Acad Sci U S A. 2015;112:11276-81 pubmed publisher |
Kijas A, Lim Y, Bolderson E, Cerosaletti K, Gatei M, Jakob B, et al. ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1. Nucleic Acids Res. 2015;43:8352-67 pubmed publisher |
Lee K, Im J, Shibata E, Park J, Handa N, Kowalczykowski S, et al. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. Nat Commun. 2015;6:7744 pubmed publisher |
Rein K, Yanez D, Terré B, Palenzuela L, Aivio S, Wei K, et al. EXO1 is critical for embryogenesis and the DNA damage response in mice with a hypomorphic Nbs1 allele. Nucleic Acids Res. 2015;43:7371-87 pubmed publisher |
Chen W, Ebelt N, Stracker T, Xhemalce B, Van Den Berg C, Miller K. ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion. elife. 2015;4: pubmed publisher |
Goldstein M, Kastan M. Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding. Cancer Res. 2015;75:2699-707 pubmed publisher |
Vermezovic J, Adamowicz M, Santarpia L, Rustighi A, Forcato M, Lucano C, et al. Notch is a direct negative regulator of the DNA-damage response. Nat Struct Mol Biol. 2015;22:417-24 pubmed publisher |
Kobayashi J, Saito Y, Okui M, Miwa N, Komatsu K. Increased oxidative stress in AOA3 cells disturbs ATM-dependent DNA damage responses. Mutat Res Genet Toxicol Environ Mutagen. 2015;782:42-50 pubmed publisher |
Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T. Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol. 2015;89:5040-59 pubmed publisher |
Patel J, Puck J, Srinivasan R, Brown C, Sunderam U, Kundu K, et al. Nijmegen breakage syndrome detected by newborn screening for T cell receptor excision circles (TRECs). J Clin Immunol. 2015;35:227-33 pubmed publisher |
Xie M, Park D, You S, Li R, Owonikoko T, Wang Y, et al. Bcl2 inhibits recruitment of Mre11 complex to DNA double-strand breaks in response to high-linear energy transfer radiation. Nucleic Acids Res. 2015;43:960-72 pubmed publisher |
Lentz T, Samulski R. Insight into the mechanism of inhibition of adeno-associated virus by the Mre11/Rad50/Nbs1 complex. J Virol. 2015;89:181-94 pubmed publisher |
Faller E, McVey M, MacPherson P. IL-7 receptor recovery on CD8 T-cells isolated from HIV+ patients is inhibited by the HIV Tat protein. PLoS ONE. 2014;9:e102677 pubmed publisher |
Larbi A, Mitjavila Garcia M, Flamant S, Valogne Y, Clay D, Usunier B, et al. Generation of multipotent early lymphoid progenitors from human embryonic stem cells. Stem Cells Dev. 2014;23:2983-95 pubmed publisher |
Munneke J, Björklund A, Mjösberg J, Garming Legert K, Bernink J, Blom B, et al. Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease. Blood. 2014;124:812-21 pubmed publisher |
Forsberg A, Bengtsson M, Eringfält A, Ernerudh J, Mjösberg J, Jenmalm M. GATA binding protein 3? group 2 innate lymphoid cells are present in cord blood and in higher proportions in male than in female neonates. J Allergy Clin Immunol. 2014;134:228-30 pubmed publisher |
Peguillet I, Milder M, Louis D, Vincent Salomon A, Dorval T, Piperno Neumann S, et al. High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer. Cancer Res. 2014;74:2204-16 pubmed publisher |
Sereti I, Estes J, Thompson W, Morcock D, Fischl M, Croughs T, et al. Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration. PLoS Pathog. 2014;10:e1003890 pubmed publisher |
Compeer E, Flinsenberg T, Boon L, Hoekstra M, Boes M. Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentation. J Biol Chem. 2014;289:520-8 pubmed publisher |
Yu X, Pappu R, Ramirez Carrozzi V, Ota N, Caplazi P, Zhang J, et al. TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriers. Mucosal Immunol. 2014;7:730-40 pubmed publisher |
Lozza L, Farinacci M, Faé K, Bechtle M, Stäber M, Dorhoi A, et al. Crosstalk between human DC subsets promotes antibacterial activity and CD8+ T-cell stimulation in response to bacille Calmette-Guérin. Eur J Immunol. 2014;44:80-92 pubmed publisher |
Ponchel F, Goeb V, Parmar R, El Sherbiny Y, Boissinot M, El Jawhari J, et al. An immunological biomarker to predict MTX response in early RA. Ann Rheum Dis. 2014;73:2047-53 pubmed publisher |
Bernink J, Peters C, Munneke M, te Velde A, Meijer S, Weijer K, et al. Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues. Nat Immunol. 2013;14:221-9 pubmed publisher |
Luckashenak N, Wähe A, Breit K, Brakebusch C, Brocker T. Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo. J Immunol. 2013;190:27-35 pubmed publisher |
Ghazawi F, Faller E, Sugden S, Kakal J, MacPherson P. IL-7 downregulates IL-7R? expression in human CD8 T cells by two independent mechanisms. Immunol Cell Biol. 2013;91:149-58 pubmed publisher |
Yatim A, Benne C, Sobhian B, Laurent Chabalier S, Déas O, Judde J, et al. NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. Mol Cell. 2012;48:445-58 pubmed publisher |
Petrovas C, Yamamoto T, Gerner M, Boswell K, Wloka K, Smith E, et al. CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest. 2012;122:3281-94 pubmed publisher |
Noakes P, Vlachava M, Kremmyda L, Diaper N, Miles E, Erlewyn Lajeunesse M, et al. Increased intake of oily fish in pregnancy: effects on neonatal immune responses and on clinical outcomes in infants at 6 mo. Am J Clin Nutr. 2012;95:395-404 pubmed publisher |
Young C, Angel J. HIV infection of thymocytes inhibits IL-7 activity without altering CD127 expression. Retrovirology. 2011;8:72 pubmed publisher |
Mjösberg J, Trifari S, Crellin N, Peters C, van Drunen C, Piet B, et al. Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat Immunol. 2011;12:1055-62 pubmed publisher |
Pankewycz O, Leca N, Kohli R, Wallace P, Said M, Feng L, et al. Low-dose rabbit antithymocyte globulin induction therapy results in prolonged selective lymphocyte depletion irrespective of maintenance immunosuppression. Transplant Proc. 2011;43:462-5 pubmed publisher |
van Roon J, Hartgring S, van der Wurff Jacobs K, Bijlsma J, Lafeber F. Numbers of CD25+Foxp3+ T cells that lack the IL-7 receptor are increased intra-articularly and have impaired suppressive function in RA patients. Rheumatology (Oxford). 2010;49:2084-9 pubmed publisher |
Engram J, Cervasi B, Borghans J, Klatt N, Gordon S, Chahroudi A, et al. Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates. Blood. 2010;116:748-58 pubmed publisher |
Crawley A, Faucher S, Angel J. Soluble IL-7R alpha (sCD127) inhibits IL-7 activity and is increased in HIV infection. J Immunol. 2010;184:4679-87 pubmed publisher |
Presicce P, Moreno Fernandez M, Lages C, Orsborn K, Chougnet C. Association of two clones allows for optimal detection of human FOXP3. Cytometry A. 2010;77:571-9 pubmed publisher |
Valencia J, Hernández López C, Martínez V, Hidalgo L, Zapata A, Vicente A, et al. Transient beta-catenin stabilization modifies lineage output from human thymic CD34+CD1a- progenitors. J Leukoc Biol. 2010;87:405-14 pubmed publisher |
Portevin D, Poupot M, Rolland O, Turrin C, Fournie J, Majoral J, et al. Regulatory activity of azabisphosphonate-capped dendrimers on human CD4+ T cell proliferation enhances ex-vivo expansion of NK cells from PBMCs for immunotherapy. J Transl Med. 2009;7:82 pubmed publisher |
Vudattu N, Kuhlmann Berenzon S, Khademi M, Seyfert V, Olsson T, Maeurer M. Increased numbers of IL-7 receptor molecules on CD4+CD25-CD107a+ T-cells in patients with autoimmune diseases affecting the central nervous system. PLoS ONE. 2009;4:e6534 pubmed publisher |
Sauce D, Larsen M, Abbott R, Hislop A, Leese A, Khan N, et al. Upregulation of interleukin 7 receptor alpha and programmed death 1 marks an epitope-specific CD8+ T-cell response that disappears following primary Epstein-Barr virus infection. J Virol. 2009;83:9068-78 pubmed publisher |
Łuczyński W, Wawrusiewicz Kurylonek N, Stasiak Barmuta A, Urban R, Iłendo E, Urban M, et al. Diminished expression of ICOS, GITR and CTLA-4 at the mRNA level in T regulatory cells of children with newly diagnosed type 1 diabetes. Acta Biochim Pol. 2009;56:361-70 pubmed |
Faller E, Kakal J, Kumar R, MacPherson P. IL-7 and the HIV Tat protein act synergistically to down-regulate CD127 expression on CD8 T cells. Int Immunol. 2009;21:203-16 pubmed publisher |
Sharma T, Hughes J, Murillo A, Riley J, Soares A, Little F, et al. CD8+ T-cell interleukin-7 receptor alpha expression as a potential indicator of disease status in HIV-infected children. PLoS ONE. 2008;3:e3986 pubmed publisher |
Mason R, Rose R, Seddiki N, Kelleher A, Kent S. Low pre-infection levels and loss of central memory CD4+ T cells may predict rapid progression in SIV-infected pigtail macaques. Virology. 2008;381:11-5 pubmed publisher |
Johnson S, Shah N, Bajer A, Lebien T. IL-7 activates the phosphatidylinositol 3-kinase/AKT pathway in normal human thymocytes but not normal human B cell precursors. J Immunol. 2008;180:8109-17 pubmed |
Zonios D, Falloon J, Bennett J, Shaw P, Chaitt D, Baseler M, et al. Idiopathic CD4+ lymphocytopenia: natural history and prognostic factors. Blood. 2008;112:287-94 pubmed publisher |
Esquerré M, Tauzin B, Guiraud M, Müller S, Saoudi A, Valitutti S. Human regulatory T cells inhibit polarization of T helper cells toward antigen-presenting cells via a TGF-beta-dependent mechanism. Proc Natl Acad Sci U S A. 2008;105:2550-5 pubmed publisher |
Esendagli G, Bruderek K, Goldmann T, Busche A, Branscheid D, Vollmer E, et al. Malignant and non-malignant lung tissue areas are differentially populated by natural killer cells and regulatory T cells in non-small cell lung cancer. Lung Cancer. 2008;59:32-40 pubmed |
Scupoli M, Perbellini O, Krampera M, Vinante F, Cioffi F, Pizzolo G. Interleukin 7 requirement for survival of T-cell acute lymphoblastic leukemia and human thymocytes on bone marrow stroma. Haematologica. 2007;92:264-6 pubmed |
Hartigan O Connor D, Poon C, Sinclair E, McCune J. Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells. J Immunol Methods. 2007;319:41-52 pubmed publisher |
Higgins J, Metcalf J, Stevens R, Baseler M, Nason M, Lane H, et al. Effects of lymphocyte isolation and timing of processing on detection of CD127 expression on T cells in human immunodeficiency virus-infected patients. Clin Diagn Lab Immunol. 2005;12:228-30 pubmed |
Ito T, Amakawa R, Inaba M, Ikehara S, Inaba K, Fukuhara S. Differential regulation of human blood dendritic cell subsets by IFNs. J Immunol. 2001;166:2961-9 pubmed |
