product summary
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company name :
Novatein Biosciences
product type :
protein
product name :
dCas9 (D10A & H840A)
catalog :
PR-137213
price :
275.00 USD
more info or order :
Novatein Biosciences product webpage
product information
Catalog Number :
PR-137213
Product Name :
dCas9 (D10A & H840A)
Product Type :
protein
List Price :
275.00 USD
Background :
The functions of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and CRISPR-associated (Cas) genes are essential in adaptive immunity in select bacteria and archaea. CRISPR uses a Cas9 protein to recognize DNA sequences, with target specificity solely determined by a small guide (sg) RNA and a protospacer adjacent motif (PAM) Upon binding to target DNA, the Cas9-sgRNA complex generates a DNA double-stranded break. Based on this RNA- guided nuclease activity, CRISPR has been showed to be a powerful tool in editing the genomes of a broad range of organisms. Furthermore, a repurposed, nuclease-deactivated Cas9 (dCas9) protein has been used to regulate endogenous gene expression and labeling of genomic loci in living and fixed cells.
Concentration :
1 μg/μl
Storage :
-20°C. Avoid freeze thaw cycles.
more info or order :
Novatein Biosciences product webpage
company information
Novatein Biosciences
310 West Cummings Park
Woburn, MA 01801
www.novateinbio.com
(617) 238-1396
(888) 856-2858
headquarters: US