AMACR | Nordic BioSite BSH-7136-100 product information

product summary

company name :

Nordic BioSite

product type :

antibody

product name :

AMACR

catalog :

BSH-7136-100

quantity :

100 µl

price :

190 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

BS2

reactivity :

human, mouse

application :

immunohistochemistry - paraffin section

more info or order :

Nordic BioSite product webpage

product information

Catalog Number :

BSH-7136-100

Product Name :

AMACR

Product Type :

Antibodies, Primary

Host Species :

mouse

Clonality :

monoclonal

Conjugation :

Unconjugated

Clone Name :

BS2

Size :

100 µl

List Price (USD) :

190 USD

Product Description :

Anti-AMACR, mouse monoclonal - Optibodies

Background :

AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. AMACR can be used as a positive marker for PIN. Defects in AMACR are the cause of congenital bile acid synthesis defect type 4 (CBAS4); also known as cholestasis, intrahepatic, with defective conversion of trihydroxycoprostanic acid to cholic acid or trihydroxycoprostanic acid in bile. Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile.

ALTnames :

Alpha-methylacyl-CoA racemase

Buffer :

TRIS with 0.03% sodium azide, pH7,2

Application Summary :

IHC-P

Storage :

Store at 4℃

more info or order :

Nordic BioSite product webpage