CK5 (CK-HMW) | Nordic BioSite BSH-3011-1 product information

product summary

company name :

Nordic BioSite

product type :

antibody

product name :

CK5 (CK-HMW)

catalog :

BSH-3011-1

quantity :

1 ml

price :

550 USD

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

BSR55

reactivity :

human

application :

immunohistochemistry - paraffin section

more info or order :

Nordic BioSite product webpage

product information

Catalog Number :

BSH-3011-1

Product Name :

CK5 (CK-HMW)

Product Type :

Antibodies, Primary

Host Species :

rabbit

Clonality :

monoclonal

Conjugation :

Unconjugated

Clone Name :

BSR55

Size :

1 ml

List Price (USD) :

550 USD

Product Description :

Anti-Cytokeratin 5 (CK-HMW), rabbit monoclonal - Optibodies

Background :

CK5 (keratin 5) is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.

ALTnames :

KRT5

Buffer :

TRIS with 0.03% sodium azide, pH7,2

Application Summary :

IHC-P

Storage :

Store at 4℃

more info or order :

Nordic BioSite product webpage