product summary
Loading...
company name :
Nordic BioSite
product type :
antibody
product name :
CD117
catalog :
ARM-20010
quantity :
100 uL
price :
85 USD
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
YR145
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
product information
Catalog Number :
ARM-20010
Product Name :
CD117
Product Type :
Antibodies, Primary
Host Species :
rabbit
Clonality :
monoclonal
Conjugation :
Unconjugated
Clone Name :
YR145
Size :
100 uL
List Price (USD) :
85 USD
Product Description :
Anti-CD117, C-Term, rabbit monoclonal antibody
Background :
Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1 (1-2), c-Kit is a cellular homologue of the oncogene v-Kit of the Hardy Zuckerman 4-feline sarcoma virus (3). Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K (4). Missense substitution within the cellular tyrosine kinase may cause Piebaldism an autosomal dominant disorder of the skin (5).
ALTnames :
ckit, SCFR, Proto-oncogene tyrosine-protein kinase Kit, c-kit, CD117 antigen, PBT
Immunogen :
A synthetic peptide corresponding to residues in the C-terminus (cytoplasmic domain) of human c-Kit was used as an immunogen. The antibody does not cross-react with other CSF-1/PDGF receptor family member.
Application Summary :
IHC,WB
Storage :
Store at 4℃
more info or order :
company information
Nordic BioSite
support-us@nordicbiosite.com
www.nordicbiosite.comrelated products
browse more products
questions and comments