product summary
company name :
Neuromab
product type :
antibody
product name :
GluN1/NR1 glutamate receptor
catalog :
75-272
quantity :
100 ug
price :
319 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N308/48
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 2c
Koster K, Francesconi W, Berton F, Alahmadi S, Srinivas R, Yoshii A. Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 5c
Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed publisher
  • western blot; mouse; fig 6
Vingtdeux V, Chang E, Frattini S, Zhao H, Chandakkar P, Adrien L, et al. CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice. Sci Rep. 2016;6:24250 pubmed publisher
  • immunohistochemistry; rat; 5 ug/ml; loading ...; fig 7a
Balsara R, Dang A, Donahue D, Snow T, Castellino F. Conantokin-G attenuates detrimental effects of NMDAR hyperactivity in an ischemic rat model of stroke. PLoS ONE. 2015;10:e0122840 pubmed publisher
  • immunohistochemistry; mouse; 1:500
de Andrade G, Kunzelman L, Merrill M, Fuerst P. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. Mol Vis. 2014;20:1422-33 pubmed
  • western blot; human; 1:300; fig 1
Maraschi A, Ciammola A, Folci A, Sassone F, Ronzitti G, Cappelletti G, et al. Parkin regulates kainate receptors by interacting with the GluK2 subunit. Nat Commun. 2014;5:5182 pubmed publisher
Moraga Amaro R, González H, Ugalde V, Donoso Ramos J, Quintana Donoso D, Lara M, et al. Dopamine receptor D5 deficiency results in a selective reduction of hippocampal NMDA receptor subunit NR2B expression and impaired memory. Neuropharmacology. 2016;103:222-35 pubmed publisher
Lee N, Song J, Cho H, Sung Y, Lee T, Chung A, et al. Hexa (ethylene glycol) derivative of benzothiazole aniline promotes dendritic spine formation through the RasGRF1-Ras dependent pathway. Biochim Biophys Acta. 2016;1862:284-95 pubmed publisher
Lv J, Guo X, Chen B, Lei Q, Pan Y, Yang Q. The Noncompetitive AMPAR Antagonist Perampanel Abrogates Brain Endothelial Cell Permeability in Response to Ischemia: Involvement of Claudin-5. Cell Mol Neurobiol. 2016;36:745-53 pubmed publisher
Fourie C, Kim E, Waldvogel H, Wong J, McGregor A, Faull R, et al. Differential Changes in Postsynaptic Density Proteins in Postmortem Huntington's Disease and Parkinson's Disease Human Brains. J Neurodegener Dis. 2014;2014:938530 pubmed publisher
Dibattista A, Dumanis S, Song J, Bu G, Weeber E, Rebeck G, et al. Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner. Biochim Biophys Acta. 2015;1853:904-17 pubmed publisher
D Orsi B, Kilbride S, Chen G, Perez Alvarez S, Bonner H, Pfeiffer S, et al. Bax regulates neuronal Ca2+ homeostasis. J Neurosci. 2015;35:1706-22 pubmed publisher
Hanson J, Pare J, Deng L, Smith Y, Zhou Q. Altered GluN2B NMDA receptor function and synaptic plasticity during early pathology in the PS2APP mouse model of Alzheimer's disease. Neurobiol Dis. 2015;74:254-62 pubmed publisher
Warmus B, Sekar D, McCutchen E, Schellenberg G, Roberts R, McMahon L, et al. Tau-mediated NMDA receptor impairment underlies dysfunction of a selectively vulnerable network in a mouse model of frontotemporal dementia. J Neurosci. 2014;34:16482-95 pubmed publisher
Gomez A, Froemke R, Burden S. Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. elife. 2014;3:e04287 pubmed publisher
Carney K, Milanese M, Van Nierop P, Li K, Oliet S, Smit A, et al. Proteomic analysis of gliosomes from mouse brain: identification and investigation of glial membrane proteins. J Proteome Res. 2014;13:5918-27 pubmed publisher
Yan Y, Eipper B, Mains R. Kalirin-9 and Kalirin-12 Play Essential Roles in Dendritic Outgrowth and Branching. Cereb Cortex. 2015;25:3487-501 pubmed publisher
Gunn B, Cunningham L, Cooper M, Corteen N, Seifi M, Swinny J, et al. Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress response. J Neurosci. 2013;33:19534-54 pubmed publisher
Luo P, Yang Y, Liu W, Rao W, Bian H, Li X, et al. Downregulation of postsynaptic density-95-interacting regulator of spine morphogenesis reduces glutamate-induced excitotoxicity by differentially regulating glutamate receptors in rat cortical neurons. FEBS J. 2013;280:6114-27 pubmed publisher
Deng Y, Xiong Z, Chen P, Wei J, Chen S, Yan Z. ?-amyloid impairs the regulation of N-methyl-D-aspartate receptors by glycogen synthase kinase 3. Neurobiol Aging. 2014;35:449-59 pubmed publisher
Duffney L, Wei J, Cheng J, Liu W, Smith K, Kittler J, et al. Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism. J Neurosci. 2013;33:15767-78 pubmed publisher
Wang X, Lippi G, Carlson D, Berg D. Activation of ?7-containing nicotinic receptors on astrocytes triggers AMPA receptor recruitment to glutamatergic synapses. J Neurochem. 2013;127:632-43 pubmed publisher
Sohn Y, Lee N, Chung A, Saavedra J, Scott Turner R, Pak D, et al. Antihypertensive drug Valsartan promotes dendritic spine density by altering AMPA receptor trafficking. Biochem Biophys Res Commun. 2013;439:464-70 pubmed publisher
Cheng J, Liu W, Duffney L, Yan Z. SNARE proteins are essential in the potentiation of NMDA receptors by group II metabotropic glutamate receptors. J Physiol. 2013;591:3935-47 pubmed publisher
Megill A, Lee T, Dibattista A, Song J, Spitzer M, Rubinshtein M, et al. A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis. J Neurosci. 2013;33:9306-18 pubmed publisher
Murata Y, Constantine Paton M. Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway. J Neurosci. 2013;33:5040-52 pubmed publisher
Deparis S, Caprara C, Grimm C. Intrinsically photosensitive retinal ganglion cells are resistant to N-methyl-D-aspartic acid excitotoxicity. Mol Vis. 2012;18:2814-27 pubmed
product information
TargetType :
Receptors
Target :
GluN1/NR1 glutamate receptor
AccessionNum :
P35439-2
Clone :
N308/48
HumanGeneName :
GRIN1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N308_48.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
ND
Catalog :
75-272
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States