LRRK2/Dardarin, N3 (non-mouse-reactive) | Neuromab 75-266 product information

product summary

company name :

Neuromab

product type :

antibody

product name :

LRRK2/Dardarin, N3 (non-mouse-reactive)

catalog :

75-266

quantity :

100 ug

price :

269 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

N231B/34

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, proximity ligation assay, western blot knockout validation, immunocytochemistry knockout validation

more info or order :

Neuromab product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry knockout validation; mouse; fig s3 immunoprecipitation; mouse; fig 2 western blot; mouse; fig 1 western blot knockout validation; rat; fig 5 immunoprecipitation; human; fig 2 western blot; human; fig 1	Davies P, Hinkle K, Sukar N, Sepulveda B, Mesias R, Serrano G, et al. Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies. Biochem J. 2013;453:101-13 pubmed publisher
proximity ligation assay; mouse; 1:50; fig 6 immunocytochemistry; mouse; 1:50; fig 6 proximity ligation assay; human; 1:50; fig s6 immunocytochemistry; human; 1:50; fig s6	Choi I, Kim B, Byun J, Baik S, Huh Y, Kim J, et al. LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase. Nat Commun. 2015;6:8255 pubmed publisher
	Belluzzi E, Gonnelli A, Cirnaru M, Marte A, Plotegher N, Russo I, et al. LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate. Mol Neurodegener. 2016;11:1 pubmed publisher
	Daher J, Volpicelli Daley L, Blackburn J, Moehle M, West A. Abrogation of ?-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats. Proc Natl Acad Sci U S A. 2014;111:9289-94 pubmed publisher
	Dorval V, Mandemakers W, Jolivette F, Coudert L, Mazroui R, De Strooper B, et al. Gene and MicroRNA transcriptome analysis of Parkinson's related LRRK2 mouse models. PLoS ONE. 2014;9:e85510 pubmed publisher

product information

TargetType :

Other

Target :

LRRK2/Dardarin, N3 (non-mouse-reactive)

AccessionNum :

Q5S007

Clone :

N231B/34

HumanGeneName :

LRRK2

DataSheetFileName :

neuromab.ucdavis.edu/datasheet/N231B_34.pdf

IsoType :

IgG2a

ValidationT :

Pass

ValidationBrIB :

Pass

ValidationBrIHC :

Pass

ValidationKO :

Pass

Catalog :

75-266

more info or order :

Neuromab product webpage