product summary
company name :
Neuromab
product type :
antibody
product name :
TRIP8b (constant)
catalog :
75-244
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N212/17
reactivity :
rat
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
citations: 5
Reference
Lyman K, Han Y, Heuermann R, Cheng X, Kurz J, Lyman R, et al. Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels. J Biol Chem. 2017;292:17718-17730 pubmed publisher
Kupferman J, Basu J, Russo M, Guevarra J, Cheung S, Siegelbaum S. Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment. Cell. 2014;158:1335-1347 pubmed publisher
Wilkars W, Wollberg J, Mohr E, Han M, Chetkovich D, Bähring R, et al. Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels. FASEB J. 2014;28:2177-90 pubmed publisher
Wilkars W, Liu Z, Lewis A, Stoub T, Ramos E, Brandt N, et al. Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms. PLoS ONE. 2012;7:e32181 pubmed publisher
Piskorowski R, Santoro B, Siegelbaum S. TRIP8b splice forms act in concert to regulate the localization and expression of HCN1 channels in CA1 pyramidal neurons. Neuron. 2011;70:495-509 pubmed publisher
product information
TargetType :
Ion channels
Target :
TRIP8b (constant)
AccessionNum :
Q925N3
Clone :
N212/17
HumanGeneName :
PEX5L
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N212_17.pdf
IsoType :
IgG2a
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
75-244
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States