product summary
company name :
Neuromab
product type :
antibody
product name :
LRP4 (extracellular)
catalog :
75-221
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N207/27
reactivity :
mouse
application :
western blot, immunocytochemistry, blocking or activating experiments, western blot knockout validation
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; fig 5
Sun X, Li L, Liu F, Huang Z, Bean J, Jiao H, et al. Lrp4 in astrocytes modulates glutamatergic transmission. Nat Neurosci. 2016;19:1010-8 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3s1c
Zhang H, Sathyamurthy A, Liu F, Li L, Zhang L, Dong Z, et al. Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice. elife. 2019;8: pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig 8c
Wang K, Lin M, Adelman J, Maylie J. Distinct Ca2+ sources in dendritic spines of hippocampal CA1 neurons couple to SK and Kv4 channels. Neuron. 2014;81:379-87 pubmed publisher
Xiong L, Jung J, Guo H, Pan J, Sun X, Mei L, et al. Osteoblastic Lrp4 promotes osteoclastogenesis by regulating ATP release and adenosine-A2AR signaling. J Cell Biol. 2017;216:761-778 pubmed publisher
Gomez A, Froemke R, Burden S. Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. elife. 2014;3:e04287 pubmed publisher
Barik A, Lu Y, Sathyamurthy A, Bowman A, Shen C, Li L, et al. LRP4 is critical for neuromuscular junction maintenance. J Neurosci. 2014;34:13892-905 pubmed publisher
Shen C, Lu Y, Zhang B, Figueiredo D, Bean J, Jung J, et al. Antibodies against low-density lipoprotein receptor-related protein 4 induce myasthenia gravis. J Clin Invest. 2013;123:5190-202 pubmed publisher
Wu H, Lu Y, Shen C, Patel N, Gan L, Xiong W, et al. Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation. Neuron. 2012;75:94-107 pubmed publisher
product information
TargetType :
Receptors
Target :
LRP4 (extracellular)
AccessionNum :
Q8VI56
Clone :
N207/27
HumanGeneName :
LRP4
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N207_27.pdf
IsoType :
IgG2a
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
ND
ValidationKO :
ND
Catalog :
75-221
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States