product summary
company name :
Neuromab
product type :
antibody
product name :
Kv2.1 K+ channel (external)
catalog :
75-159
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
K39/25
reactivity :
human, mouse
application :
western blot, immunocytochemistry
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse
Nieves Cintrón M, Nystoriak M, Prada M, Johnson K, Fayer W, Dell Acqua M, et al. Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes. J Biol Chem. 2015;290:7918-29 pubmed publisher
Frazzini V, Guarnieri S, Bomba M, Navarra R, Morabito C, Mariggiò M, et al. Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer's disease mouse model. Cell Death Dis. 2016;7:e2100 pubmed publisher
David J, Stas J, Schmitt N, Bocksteins E. Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels. Sci Rep. 2015;5:12813 pubmed publisher
Zhao X, Kuja Panula J, Sundvik M, Chen Y, Aho V, Peltola M, et al. Amigo adhesion protein regulates development of neural circuits in zebrafish brain. J Biol Chem. 2014;289:19958-75 pubmed publisher
Battonyai I, Krajcs N, Serfozo Z, Kiss T, Elekes K. Potassium channels in the central nervous system of the snail, Helix pomatia: localization and functional characterization. Neuroscience. 2014;268:87-101 pubmed publisher
Kirizs T, Kerti Szigeti K, Lorincz A, Nusser Z. Distinct axo-somato-dendritic distributions of three potassium channels in CA1 hippocampal pyramidal cells. Eur J Neurosci. 2014;39:1771-83 pubmed publisher
Jensen C, Watanabe S, Rasmussen H, Schmitt N, Olesen S, Frost N, et al. Specific sorting and post-Golgi trafficking of dendritic potassium channels in living neurons. J Biol Chem. 2014;289:10566-81 pubmed publisher
Lopez Izquierdo A, Pereira R, Wende A, Punske B, Abel E, Tristani Firouzi M. The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization. Am J Physiol Heart Circ Physiol. 2014;306:H747-54 pubmed publisher
Marionneau C, Carrasquillo Y, Norris A, Townsend R, Isom L, Link A, et al. The sodium channel accessory subunit Nav?1 regulates neuronal excitability through modulation of repolarizing voltage-gated K? channels. J Neurosci. 2012;32:5716-27 pubmed publisher
Peltola M, Kuja Panula J, Lauri S, Taira T, Rauvala H. AMIGO is an auxiliary subunit of the Kv2.1 potassium channel. EMBO Rep. 2011;12:1293-9 pubmed publisher
Plant L, Dowdell E, Dementieva I, Marks J, Goldstein S. SUMO modification of cell surface Kv2.1 potassium channels regulates the activity of rat hippocampal neurons. J Gen Physiol. 2011;137:441-54 pubmed publisher
Cheng L, Yung A, Covarrubias M, Radice G. Cortactin is required for N-cadherin regulation of Kv1.5 channel function. J Biol Chem. 2011;286:20478-89 pubmed publisher
Nataraj K, Le Roux N, Nahmani M, Lefort S, Turrigiano G. Visual deprivation suppresses L5 pyramidal neuron excitability by preventing the induction of intrinsic plasticity. Neuron. 2010;68:750-62 pubmed publisher
Hermanstyne T, Kihira Y, Misono K, Deitchler A, Yanagawa Y, Misonou H. Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice. J Comp Neurol. 2010;518:4298-310 pubmed publisher
Bocksteins E, Labro A, Mayeur E, Bruyns T, Timmermans J, Adriaensen D, et al. Conserved negative charges in the N-terminal tetramerization domain mediate efficient assembly of Kv2.1 and Kv2.1/Kv6.4 channels. J Biol Chem. 2009;284:31625-34 pubmed publisher
Mohapatra D, Siino D, Trimmer J. Interdomain cytoplasmic interactions govern the intracellular trafficking, gating, and modulation of the Kv2.1 channel. J Neurosci. 2008;28:4982-94 pubmed publisher
product information
TargetType :
K+ channels
Target :
Kv2.1 K+ channel (external)
AccessionNum :
Q14721
Clone :
K39/25
HumanGeneName :
KCNB1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/K39_25.pdf
IsoType :
IgG2a
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
ND
ValidationKO :
ND
Catalog :
75-159
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States