product summary
company name :
Neuromab
product type :
antibody
product name :
GABA(A)R, Beta3
catalog :
75-149
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N87/25
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section, immunohistochemistry - free floating section, immunocytochemistry knockout validation
more info or order :
citations: 26
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry knockout validation; mouse; 1:1000; loading ...; fig 1d
Duan J, Pandey S, Li T, Castellano D, Gu X, Li J, et al. Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development. Front Cell Neurosci. 2019;13:217 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Fu Y, Zhang B, Mu T. LMAN1 (ERGIC-53) promotes trafficking of neuroreceptors. Biochem Biophys Res Commun. 2019;511:356-362 pubmed publisher
  • western blot; mouse; 1:500; fig s7e
Sterky F, Trotter J, Lee S, Recktenwald C, Du X, Zhou B, et al. Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand. Proc Natl Acad Sci U S A. 2017;114:E1253-E1262 pubmed publisher
  • immunohistochemistry; rat; 1:200; loading ...; fig 4e
Wagner F, Bernard R, Derst C, French L, Veh R. Microarray analysis of transcripts with elevated expressions in the rat medial or lateral habenula suggest fast GABAergic excitation in the medial habenula and habenular involvement in the regulation of feeding and energy balance. Brain Struct Funct. 2016;221:4663-4689 pubmed
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 4
He Q, Duguid I, Clark B, Panzanelli P, Patel B, Thomas P, et al. Interneuron- and GABA(A) receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells. Nat Commun. 2015;6:7364 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:5
King A, Manning C, Trimmer J. A unique ion channel clustering domain on the axon initial segment of mammalian neurons. J Comp Neurol. 2014;522:2594-608 pubmed publisher
Mele M, Aspromonte M, Duarte C. Downregulation of GABAA Receptor Recycling Mediated by HAP1 Contributes to Neuronal Death in In Vitro Brain Ischemia. Mol Neurobiol. 2017;54:45-57 pubmed publisher
Babateen O, Jin Z, Bhandage A, Korol S, Westermark B, Forsberg Nilsson K, et al. Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from human glioblastoma. Eur J Pharmacol. 2015;748:101-7 pubmed publisher
Marty V, Vlkolinsky R, Minassian N, Cohen T, Nelson G, Spigelman I. Radiation-induced alterations in synaptic neurotransmission of dentate granule cells depend on the dose and species of charged particles. Radiat Res. 2014;182:653-65 pubmed publisher
Mele M, Ribeiro L, Inácio A, Wieloch T, Duarte C. GABA(A) receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia. Neurobiol Dis. 2014;65:220-32 pubmed publisher
Han K, Holder J, Schaaf C, Lu H, Chen H, Kang H, et al. SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties. Nature. 2013;503:72-7 pubmed publisher
Pribiag H, Stellwagen D. TNF-? downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors. J Neurosci. 2013;33:15879-93 pubmed publisher
Zhou C, Huang Z, Ding L, Deel M, Arain F, Murray C, et al. Altered cortical GABAA receptor composition, physiology, and endocytosis in a mouse model of a human genetic absence epilepsy syndrome. J Biol Chem. 2013;288:21458-72 pubmed publisher
Alicea B, Murthy S, Keaton S, Cobbett P, Cibelli J, Suhr S. Defining the diversity of phenotypic respecification using multiple cell lines and reprogramming regimens. Stem Cells Dev. 2013;22:2641-54 pubmed publisher
Fuks J, Arrighi R, Weidner J, Kumar Mendu S, Jin Z, Wallin R, et al. GABAergic signaling is linked to a hypermigratory phenotype in dendritic cells infected by Toxoplasma gondii. PLoS Pathog. 2012;8:e1003051 pubmed publisher
Mendu S, Bhandage A, Jin Z, Birnir B. Different subtypes of GABA-A receptors are expressed in human, mouse and rat T lymphocytes. PLoS ONE. 2012;7:e42959 pubmed publisher
Eyre M, Renzi M, Farrant M, Nusser Z. Setting the time course of inhibitory synaptic currents by mixing multiple GABA(A) receptor α subunit isoforms. J Neurosci. 2012;32:5853-67 pubmed publisher
Sümegi M, Fukazawa Y, Matsui K, Lorincz A, Eyre M, Nusser Z, et al. Virus-mediated swapping of zolpidem-insensitive with zolpidem-sensitive GABA(A) receptors in cortical pyramidal cells. J Physiol. 2012;590:1517-34 pubmed publisher
Gurba K, Hernandez C, Hu N, Macdonald R. GABRB3 mutation, G32R, associated with childhood absence epilepsy alters ?1?3?2L ?-aminobutyric acid type A (GABAA) receptor expression and channel gating. J Biol Chem. 2012;287:12083-97 pubmed publisher
Kerti K, Lorincz A, Nusser Z. Unique somato-dendritic distribution pattern of Kv4.2 channels on hippocampal CA1 pyramidal cells. Eur J Neurosci. 2012;35:66-75 pubmed publisher
Yanovsky Y, Schubring S, Fleischer W, Gisselmann G, Zhu X, Lübbert H, et al. GABAA receptors involved in sleep and anaesthesia: ?1- versus ?3-containing assemblies. Pflugers Arch. 2012;463:187-99 pubmed publisher
Jo Y, Donier E, Martinez A, Garret M, Toulme E, Boué Grabot E. Cross-talk between P2X4 and gamma-aminobutyric acid, type A receptors determines synaptic efficacy at a central synapse. J Biol Chem. 2011;286:19993-20004 pubmed publisher
Fagerlund M, Kåhlin J, Ebberyd A, Schulte G, Mkrtchian S, Eriksson L. The human carotid body: expression of oxygen sensing and signaling genes of relevance for anesthesia. Anesthesiology. 2010;113:1270-9 pubmed publisher
Adusei D, Pacey L, Chen D, Hampson D. Early developmental alterations in GABAergic protein expression in fragile X knockout mice. Neuropharmacology. 2010;59:167-71 pubmed publisher
Smith K, Oliver P, Lumb M, Arancibia Carcamo I, Revilla Sanchez R, Brandon N, et al. Identification and characterisation of a Maf1/Macoco protein complex that interacts with GABAA receptors in neurons. Mol Cell Neurosci. 2010;44:330-41 pubmed publisher
Arancibia Carcamo I, Yuen E, Muir J, Lumb M, Michels G, Saliba R, et al. Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition. Proc Natl Acad Sci U S A. 2009;106:17552-7 pubmed publisher
product information
TargetType :
Receptors
Target :
GABA(A)R, Beta3
AccessionNum :
P63080
Clone :
N87/25
HumanGeneName :
GABRB3
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N87_25.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
ND
Catalog :
75-149
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States