product summary
company name :
Neuromab
product type :
antibody
product name :
Ankyrin-B
catalog :
75-145
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N105/17
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; 1:500; loading ...; fig 6s2b
  • western blot; human; 1:2000; loading ...; fig 7s1a
Yang H, Pérez Hernández M, Sanchez Alonso J, Shevchuk A, Gorelik J, Rothenberg E, et al. Ankyrin-G mediates targeting of both Na+ and KATP channels to the rat cardiac intercalated disc. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:100; loading ...; fig 5s2
Wang G, Simon D, Wu Z, Belsky D, Heller E, O Rourke M, et al. Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 6c
Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2a
Mooney C, Jimenez Mateos E, Engel T, Mooney C, Diviney M, Venø M, et al. RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis. Sci Rep. 2017;7:41517 pubmed publisher
  • immunohistochemistry; mouse; fig 8
Le Bras B, Fréal A, Czarnecki A, Legendre P, Bullier E, Komada M, et al. In vivo assembly of the axon initial segment in motor neurons. Brain Struct Funct. 2014;219:1433-50 pubmed publisher
Susuki K, Zollinger D, Chang K, Zhang C, Huang C, Tsai C, et al. Glial βII Spectrin Contributes to Paranode Formation and Maintenance. J Neurosci. 2018;38:6063-6075 pubmed publisher
Ho T, Zollinger D, Chang K, Xu M, Cooper E, Stankewich M, et al. A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier. Nat Neurosci. 2014;17:1664-72 pubmed publisher
Chang K, Zollinger D, Susuki K, Sherman D, Makara M, Brophy P, et al. Glial ankyrins facilitate paranodal axoglial junction assembly. Nat Neurosci. 2014;17:1673-81 pubmed publisher
Zhang C, Susuki K, Zollinger D, Dupree J, Rasband M. Membrane domain organization of myelinated axons requires ?II spectrin. J Cell Biol. 2013;203:437-43 pubmed publisher
Galiano M, Jha S, Ho T, Zhang C, Ogawa Y, Chang K, et al. A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly. Cell. 2012;149:1125-39 pubmed publisher
Kaphzan H, Buffington S, Jung J, Rasband M, Klann E. Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome. J Neurosci. 2011;31:17637-48 pubmed publisher
Lysakowski A, Gaboyard Niay S, Calin Jageman I, Chatlani S, Price S, Eatock R. Molecular microdomains in a sensory terminal, the vestibular calyx ending. J Neurosci. 2011;31:10101-14 pubmed publisher
Susuki K, Raphael A, Ogawa Y, Stankewich M, Peles E, Talbot W, et al. Schwann cell spectrins modulate peripheral nerve myelination. Proc Natl Acad Sci U S A. 2011;108:8009-14 pubmed publisher
Huff T, Shi Y, Sun W, Wu W, Shi R, Cheng J. Real-time CARS imaging reveals a calpain-dependent pathway for paranodal myelin retraction during high-frequency stimulation. PLoS ONE. 2011;6:e17176 pubmed publisher
product information
TargetType :
Scaffolds
Target :
Ankyrin-B
AccessionNum :
Q01484
Clone :
N105/17
HumanGeneName :
ANK2
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N105_17.pdf
IsoType :
IgG2a
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
ND
Catalog :
75-145
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States