product summary
company name :
Neuromab
product type :
antibody
product name :
Ataxin-1, 11NQ
catalog :
75-122
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N76/3
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
citations: 4
Reference
Venkatraman A, Hu Y, Didonna A, Cvetanovic M, Krbanjevic A, Bilesimo P, et al. The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1. Hum Mol Genet. 2014;23:3733-45 pubmed publisher
Bergeron D, Lapointe C, Bissonnette C, Tremblay G, Motard J, Roucou X. An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein. J Biol Chem. 2013;288:21824-35 pubmed publisher
Park J, Al Ramahi I, Tan Q, Mollema N, Diaz Garcia J, Gallego Flores T, et al. RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1. Nature. 2013;498:325-331 pubmed publisher
Zhang C, Browne A, Child D, Divito J, Stevenson J, Tanzi R. Loss of function of ATXN1 increases amyloid beta-protein levels by potentiating beta-secretase processing of beta-amyloid precursor protein. J Biol Chem. 2010;285:8515-26 pubmed publisher
product information
TargetType :
Rare Disease
Target :
Ataxin-1, 11NQ
AccessionNum :
P54254
Clone :
N76/3
HumanGeneName :
ATXN1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N76_3.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
75-122
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States