product summary
company name :
Neuromab
product type :
antibody
product name :
Kv7.4/KCNQ4 K+ channel
catalog :
75-082
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N43/6
reactivity :
human, rat
application :
western blot, immunocytochemistry, immunohistochemistry - free floating section
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - free floating section; rat; 1:400-800
Salomonsson M, Brasen J, Braunstein T, Hagelqvist P, Holstein Rathlou N, Sorensen C. K(V)7.4 channels participate in the control of rodent renal vascular resting tone. Acta Physiol (Oxf). 2015;214:402-14 pubmed publisher
  • western blot; human; 1:500
Zhang X, Hughes B. KCNQ and KCNE potassium channel subunit expression in bovine retinal pigment epithelium. Exp Eye Res. 2013;116:424-32 pubmed
Jepps T, Olesen S, Greenwood I, Dalsgaard T. Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats. Br J Pharmacol. 2016;173:1478-90 pubmed publisher
Testai L, Barrese V, Soldovieri M, Ambrosino P, Martelli A, Vinciguerra I, et al. Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection. Cardiovasc Res. 2016;110:40-50 pubmed publisher
Sihn C, Kim H, Woltz R, Yarov Yarovoy V, Yang P, Xu J, et al. Mechanisms of Calmodulin Regulation of Different Isoforms of Kv7.4 K+ Channels. J Biol Chem. 2016;291:2499-509 pubmed publisher
Jepps T, Carr G, Lundegaard P, Olesen S, Greenwood I. Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone. J Physiol. 2015;593:5325-40 pubmed publisher
Sedivy V, Joshi S, Ghaly Y, Mizera R, Žaloudíková M, Brennan S, et al. Role of Kv7 channels in responses of the pulmonary circulation to hypoxia. Am J Physiol Lung Cell Mol Physiol. 2015;308:L48-57 pubmed publisher
Iannotti F, Silvestri C, Mazzarella E, Martella A, Calvigioni D, Piscitelli F, et al. The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels. Proc Natl Acad Sci U S A. 2014;111:E2472-81 pubmed publisher
Adduci A, Martire M, Taglialatela M, Arena V, Rizzo G, Coco C, et al. Expression and motor functional roles of voltage-dependent type 7 K(+) channels in the human taenia coli. Eur J Pharmacol. 2013;721:12-20 pubmed publisher
Evseev A, Semenov I, Archer C, Medina J, Dube P, Shapiro M, et al. Functional effects of KCNQ K(+) channels in airway smooth muscle. Front Physiol. 2013;4:277 pubmed publisher
David J, Andersen M, Olesen S, Rasmussen H, Schmitt N. Trafficking of the IKs -complex in MDCK cells: site of subunit assembly and determinants of polarized localization. Traffic. 2013;14:399-411 pubmed publisher
Iannotti F, Barrese V, Formisano L, Miceli F, Taglialatela M. Specification of skeletal muscle differentiation by repressor element-1 silencing transcription factor (REST)-regulated Kv7.4 potassium channels. Mol Biol Cell. 2013;24:274-84 pubmed publisher
Svalø J, Hansen H, Rønn L, Sheykhzade M, Munro G, Rode F. Kv 7 positive modulators reduce detrusor overactivity and increase bladder capacity in rats. Basic Clin Pharmacol Toxicol. 2012;110:145-53 pubmed publisher
Kim H, Lv P, Sihn C, Yamoah E. Cellular and molecular mechanisms of autosomal dominant form of progressive hearing loss, DFNA2. J Biol Chem. 2011;286:1517-27 pubmed publisher
Iannotti F, Panza E, Barrese V, Viggiano D, Soldovieri M, Taglialatela M. Expression, localization, and pharmacological role of Kv7 potassium channels in skeletal muscle proliferation, differentiation, and survival after myotoxic insults. J Pharmacol Exp Ther. 2010;332:811-20 pubmed publisher
product information
TargetType :
K+ channels
Target :
Kv7.4/KCNQ4 K+ channel
AccessionNum :
P56696
Clone :
N43/6
HumanGeneName :
KCNQ4
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N43_6.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
ND
ValidationKO :
ND
Catalog :
75-082
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States