product summary
company name :
Neuromab
product type :
antibody
product name :
Shank1
catalog :
75-064
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N22/21
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 7
Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher
  • western blot; rat; 1:20
Farley M, Swulius M, Waxham M. Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities. Neuroscience. 2015;304:286-301 pubmed publisher
MacGillavry H, Kerr J, Kassner J, Frost N, Blanpied T. Shank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapses. Eur J Neurosci. 2016;43:179-93 pubmed publisher
Schreiber J, Végh M, Dawitz J, Kroon T, Loos M, Labonté D, et al. Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels. J Cell Biol. 2015;211:569-86 pubmed publisher
Braude J, Vijayakumar S, Baumgarner K, Laurine R, Jones T, Jones S, et al. Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear. Hear Res. 2015;321:52-64 pubmed publisher
Han K, Holder J, Schaaf C, Lu H, Chen H, Kang H, et al. SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties. Nature. 2013;503:72-7 pubmed publisher
Catarino T, Ribeiro L, Santos S, Carvalho A. Regulation of synapse composition by protein acetylation: the role of acetylated cortactin. J Cell Sci. 2013;126:149-62 pubmed publisher
Verpelli C, Dvoretskova E, Vicidomini C, Rossi F, Chiappalone M, Schoen M, et al. Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses. J Biol Chem. 2011;286:34839-50 pubmed publisher
product information
TargetType :
Scaffolds
Target :
Shank1
AccessionNum :
Q9WV48
Clone :
N22/21
HumanGeneName :
SHANK1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N22_21.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
ND
Catalog :
75-064
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States