product summary
company name :
Neuromab
product type :
antibody
product name :
PSD-93/Chapsyn-110
catalog :
75-057
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N18/30
reactivity :
mouse, rat, rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
citations: 26
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 2g
Frank R, Zhu F, Komiyama N, Grant S. Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes. J Neurochem. 2017;142:504-511 pubmed publisher
  • immunohistochemistry; rabbit; 1:500; loading ...; tbl 1
Vila A, Whitaker C, O BRIEN J. Membrane-associated guanylate kinase scaffolds organize a horizontal cell synaptic complex restricted to invaginating contacts with photoreceptors. J Comp Neurol. 2017;525:850-867 pubmed publisher
  • western blot; mouse; 1:2500; fig 7
Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher
  • western blot; rat; 1:1000
Bustos F, Varela Nallar L, Campos M, Henriquez B, Phillips M, Opazo C, et al. PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors. PLoS ONE. 2014;9:e94037 pubmed publisher
  • western blot; rat
Murata Y, Constantine Paton M. Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway. J Neurosci. 2013;33:5040-52 pubmed publisher
Kirk L, Ti S, Bishop H, Orozco Llamas M, Pham M, Trimmer J, et al. Distribution of the SynDIG4/proline-rich transmembrane protein 1 in rat brain. J Comp Neurol. 2016;524:2266-80 pubmed publisher
Levy J, Chen X, Reese T, Nicoll R. Synaptic Consolidation Normalizes AMPAR Quantal Size following MAGUK Loss. Neuron. 2015;87:534-48 pubmed publisher
Fortin D, Tillo S, Yang G, Rah J, Melander J, Bai S, et al. Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins. J Neurosci. 2014;34:16698-712 pubmed publisher
Fujikawa T, Petralia R, Fitzgerald T, Wang Y, Millis B, Morgado Díaz J, et al. Localization of kainate receptors in inner and outer hair cell synapses. Hear Res. 2014;314:20-32 pubmed publisher
Krüger J, Favaro P, Liu M, Kitlinska A, Huang X, Raabe M, et al. Differential roles of postsynaptic density-93 isoforms in regulating synaptic transmission. J Neurosci. 2013;33:15504-17 pubmed publisher
Bonnet S, Akad D, Samaddar T, Liu Y, Huang X, Dong Y, et al. Synaptic state-dependent functional interplay between postsynaptic density-95 and synapse-associated protein 102. J Neurosci. 2013;33:13398-409 pubmed publisher
Zhao J, Murata Y, Constantine Paton M. Eye opening and PSD95 are required for long-term potentiation in developing superior colliculus. Proc Natl Acad Sci U S A. 2013;110:707-12 pubmed publisher
Ryan T, Kopanitsa M, Indersmitten T, Nithianantharajah J, Afinowi N, Pettit C, et al. Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior. Nat Neurosci. 2013;16:25-32 pubmed publisher
Shin S, Zhang N, Hansen J, Gerges N, Pak D, Sheng M, et al. GKAP orchestrates activity-dependent postsynaptic protein remodeling and homeostatic scaling. Nat Neurosci. 2012;15:1655-66 pubmed publisher
Nguyen M, Du F, Felice C, Shan X, Nigam A, Mandel G, et al. MeCP2 is critical for maintaining mature neuronal networks and global brain anatomy during late stages of postnatal brain development and in the mature adult brain. J Neurosci. 2012;32:10021-34 pubmed publisher
Zheng S, Gray E, Chawla G, Porse B, O Dell T, Black D. PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nat Neurosci. 2012;15:381-8, S1 pubmed publisher
Duflocq A, Chareyre F, Giovannini M, Couraud F, Davenne M. Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B. BMC Biol. 2011;9:66 pubmed publisher
Vacher H, Yang J, Cerda O, Autillo Touati A, Dargent B, Trimmer J. Cdk-mediated phosphorylation of the Kv?2 auxiliary subunit regulates Kv1 channel axonal targeting. J Cell Biol. 2011;192:813-24 pubmed publisher
Delint Ramirez I, Fernández E, Bayés A, Kicsi E, Komiyama N, Grant S. In vivo composition of NMDA receptor signaling complexes differs between membrane subdomains and is modulated by PSD-95 and PSD-93. J Neurosci. 2010;30:8162-70 pubmed publisher
Sumioka A, Yan D, Tomita S. TARP phosphorylation regulates synaptic AMPA receptors through lipid bilayers. Neuron. 2010;66:755-67 pubmed publisher
Yamagata M, Sanes J. Synaptic localization and function of Sidekick recognition molecules require MAGI scaffolding proteins. J Neurosci. 2010;30:3579-88 pubmed publisher
Ogawa Y, Oses Prieto J, Kim M, Horresh I, Peles E, Burlingame A, et al. ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons. J Neurosci. 2010;30:1038-48 pubmed publisher
Jeffrey R, Ch ng T, O Dell T, Martin K. Activity-dependent anchoring of importin alpha at the synapse involves regulated binding to the cytoplasmic tail of the NR1-1a subunit of the NMDA receptor. J Neurosci. 2009;29:15613-20 pubmed publisher
Chaudhury A, He X, Goyal R. Role of PSD95 in membrane association and catalytic activity of nNOSalpha in nitrergic varicosities in mice gut. Am J Physiol Gastrointest Liver Physiol. 2009;297:G806-13 pubmed publisher
Ogawa Y, Horresh I, Trimmer J, Bredt D, Peles E, Rasband M. Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2. J Neurosci. 2008;28:5731-9 pubmed publisher
Al Hallaq R, Conrads T, Veenstra T, Wenthold R. NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus. J Neurosci. 2007;27:8334-43 pubmed
product information
TargetType :
Scaffolds
Target :
PSD-93/Chapsyn-110
AccessionNum :
Q63622
Clone :
N18/30
HumanGeneName :
DLG2
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N18_30.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
75-057
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States