product summary
company name :
Neuromab
product type :
antibody
product name :
KCNU1/Slo3 maxi-K+ channel
catalog :
75-056
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N2/16
reactivity :
mouse
application :
immunocytochemistry, western blot knockout validation
more info or order :
citations: 7
Reference
Zeng X, Yang C, Xia X, Liu M, Lingle C. SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertility. Proc Natl Acad Sci U S A. 2015;112:2599-604 pubmed publisher
Yang C, Zeng X, Zhou Y, Xia X, Lingle C. LRRC52 (leucine-rich-repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel. Proc Natl Acad Sci U S A. 2011;108:19419-24 pubmed publisher
Zeng X, Yang C, Kim S, Lingle C, Xia X. Deletion of the Slo3 gene abolishes alkalization-activated K+ current in mouse spermatozoa. Proc Natl Acad Sci U S A. 2011;108:5879-84 pubmed publisher
Santi C, Martínez López P, de la Vega Beltrán J, Butler A, Alisio A, Darszon A, et al. The SLO3 sperm-specific potassium channel plays a vital role in male fertility. FEBS Lett. 2010;584:1041-6 pubmed publisher
Yang C, Zeng X, Xia X, Lingle C. Interactions between beta subunits of the KCNMB family and Slo3: beta4 selectively modulates Slo3 expression and function. PLoS ONE. 2009;4:e6135 pubmed publisher
Wang H, Liu J, Cho K, Ren D. A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein. Biol Reprod. 2009;81:539-44 pubmed publisher
Martínez López P, Santi C, Trevino C, Ocampo Gutiérrez A, Acevedo J, Alisio A, et al. Mouse sperm K+ currents stimulated by pH and cAMP possibly coded by Slo3 channels. Biochem Biophys Res Commun. 2009;381:204-9 pubmed publisher
product information
TargetType :
K+ channels
Target :
KCNU1/Slo3 maxi-K+ channel
AccessionNum :
O54982
Clone :
N2/16
HumanGeneName :
KCNU1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N2_16.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
NA
ValidationBrIHC :
NA
ValidationKO :
Pass
Catalog :
75-056
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States