product summary
company name :
Neuromab
product type :
antibody
product name :
Kv3.1b K+ channel
catalog :
75-041
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N16B/8
reactivity :
African green monkey, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; 1:100; loading ...; fig 2a, 2b
  • immunohistochemistry; African green monkey; loading ...; fig 4a
Soares D, Goldrick I, Lemon R, Kraskov A, Greensmith L, Kalmar B. Expression of Kv3.1b potassium channel is widespread in macaque motor cortex pyramidal cells: A histological comparison between rat and macaque. J Comp Neurol. 2017;525:2164-2174 pubmed publisher
Smith K, Browne L, Selwood D, McAlpine D, Jagger D. Phosphoinositide Modulation of Heteromeric Kv1 Channels Adjusts Output of Spiral Ganglion Neurons from Hearing Mice. J Neurosci. 2015;35:11221-32 pubmed publisher
Blosa M, Sonntag M, Jäger C, Weigel S, Seeger J, Frischknecht R, et al. The extracellular matrix molecule brevican is an integral component of the machinery mediating fast synaptic transmission at the calyx of Held. J Physiol. 2015;593:4341-60 pubmed publisher
Beebe K, Wang Y, Kulesza R. Distribution of fragile X mental retardation protein in the human auditory brainstem. Neuroscience. 2014;273:79-91 pubmed publisher
Bae S, Kim D, Shin S, Choi J, Park K. Src regulates membrane trafficking of the Kv3.1b channel. FEBS Lett. 2014;588:86-91 pubmed publisher
Dagley L, White C, Liao Y, Shi W, Smyth G, Orian J, et al. Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain. Proteomics. 2014;14:241-61 pubmed publisher
Jalabi W, Kopp Scheinpflug C, Allen P, Schiavon E, DiGiacomo R, Forsythe I, et al. Sound localization ability and glycinergic innervation of the superior olivary complex persist after genetic deletion of the medial nucleus of the trapezoid body. J Neurosci. 2013;33:15044-9 pubmed publisher
Hall M, Weidner D, Chen J, Bernetski C, Schwalbe R. Glycan structures contain information for the spatial arrangement of glycoproteins in the plasma membrane. PLoS ONE. 2013;8:e75013 pubmed publisher
Zhao J, Zhu J, Thornhill W. Spinocerebellar ataxia-13 Kv3.3 potassium channels: arginine-to-histidine mutations affect both functional and protein expression on the cell surface. Biochem J. 2013;454:259-65 pubmed publisher
Tong H, Kopp Scheinpflug C, Pilati N, Robinson S, Sinclair J, Steinert J, et al. Protection from noise-induced hearing loss by Kv2.2 potassium currents in the central medial olivocochlear system. J Neurosci. 2013;33:9113-21 pubmed publisher
Barry J, Xu M, Gu Y, Dangel A, Jukkola P, Shrestha C, et al. Activation of conventional kinesin motors in clusters by Shaw voltage-gated K+ channels. J Cell Sci. 2013;126:2027-41 pubmed publisher
Cotella D, Hernández Enríquez B, Duan Z, Wu X, Gazula V, Brown M, et al. An evolutionarily conserved mode of modulation of Shaw-like K? channels. FASEB J. 2013;27:1381-93 pubmed publisher
Gu Y, Barry J, McDougel R, Terman D, Gu C. Alternative splicing regulates kv3.1 polarized targeting to adjust maximal spiking frequency. J Biol Chem. 2012;287:1755-69 pubmed publisher
Shakkottai V, do Carmo Costa M, Dell Orco J, Sankaranarayanan A, Wulff H, Paulson H. Early changes in cerebellar physiology accompany motor dysfunction in the polyglutamine disease spinocerebellar ataxia type 3. J Neurosci. 2011;31:13002-14 pubmed publisher
Steinert J, Robinson S, Tong H, Haustein M, Kopp Scheinpflug C, Forsythe I. Nitric oxide is an activity-dependent regulator of target neuron intrinsic excitability. Neuron. 2011;71:291-305 pubmed publisher
Wykes R, Kalmbach A, Eliava M, Waters J. Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice. Neurobiol Aging. 2012;33:1609-23 pubmed publisher
Hall M, Cartwright T, Fleming C, Schwalbe R. Importance of glycosylation on function of a potassium channel in neuroblastoma cells. PLoS ONE. 2011;6:e19317 pubmed publisher
Song M, Moon Y, Shin S, Kim T, Yune T, Park K. Contribution of the delayed-rectifier potassium channel Kv2.1 to acute spinal cord injury in rats. BMB Rep. 2010;43:756-60 pubmed publisher
Xu M, Gu Y, Barry J, Gu C. Kinesin I transports tetramerized Kv3 channels through the axon initial segment via direct binding. J Neurosci. 2010;30:15987-6001 pubmed publisher
Strumbos J, Brown M, Kronengold J, Polley D, Kaczmarek L. Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b. J Neurosci. 2010;30:10263-71 pubmed publisher
Gittis A, Moghadam S, du Lac S. Mechanisms of sustained high firing rates in two classes of vestibular nucleus neurons: differential contributions of resurgent Na, Kv3, and BK currents. J Neurophysiol. 2010;104:1625-34 pubmed publisher
Tong H, Steinert J, Robinson S, Chernova T, Read D, Oliver D, et al. Regulation of Kv channel expression and neuronal excitability in rat medial nucleus of the trapezoid body maintained in organotypic culture. J Physiol. 2010;588:1451-68 pubmed publisher
Henderson Z, Lu C, Janzso G, Matto N, McKinley C, Yanagawa Y, et al. Distribution and role of Kv3.1b in neurons in the medial septum diagonal band complex. Neuroscience. 2010;166:952-69 pubmed publisher
Hurlock E, Bose M, Pierce G, Joho R. Rescue of motor coordination by Purkinje cell-targeted restoration of Kv3.3 channels in Kcnc3-null mice requires Kcnc1. J Neurosci. 2009;29:15735-44 pubmed publisher
Steinert J, Postlethwaite M, Jordan M, Chernova T, Robinson S, Forsythe I. NMDAR-mediated EPSCs are maintained and accelerate in time course during maturation of mouse and rat auditory brainstem in vitro. J Physiol. 2010;588:447-63 pubmed publisher
Hardman R, Forsythe I. Ether-à-go-go-related gene K+ channels contribute to threshold excitability of mouse auditory brainstem neurons. J Physiol. 2009;587:2487-97 pubmed publisher
Steinert J, Kopp Scheinpflug C, Baker C, Challiss R, Mistry R, Haustein M, et al. Nitric oxide is a volume transmitter regulating postsynaptic excitability at a glutamatergic synapse. Neuron. 2008;60:642-56 pubmed publisher
Schwalbe R, Corey M, Cartwright T. Novel Kv3 glycoforms differentially expressed in adult mammalian brain contain sialylated N-glycans. Biochem Cell Biol. 2008;86:21-30 pubmed publisher
product information
TargetType :
K+ channels
Target :
Kv3.1b K+ channel
AccessionNum :
NP_036988
Clone :
N16B/8
HumanGeneName :
KCNC1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N16B_8.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
ND
Catalog :
75-041
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States