product summary
company name :
Neuromab
product type :
antibody
product name :
PICK1
catalog :
75-040
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
L20/8
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, western blot knockout validation
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; mouse; loading ...; fig 1b
  • immunocytochemistry; mouse; loading ...; fig 1a
  • western blot; mouse; loading ...; fig 1b
Zhu J, Wang Z, Zhang N, Ma J, Xu S, Wang Y, et al. Protein Interacting C-Kinase 1 Modulates Surface Expression of P2Y6 Purinoreceptor, Actin Polymerization and Phagocytosis in Microglia. Neurochem Res. 2016;41:795-803 pubmed publisher
  • western blot; mouse; 1:1000
Hoy J, Haeger P, Constable J, Arias R, McCallum R, Kyweriga M, et al. Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions. J Neurosci. 2013;33:9364-84 pubmed publisher
Cockbill L, Murk K, Love S, Hanley J. Protein interacting with C kinase 1 suppresses invasion and anchorage-independent growth of astrocytic tumor cells. Mol Biol Cell. 2015;26:4552-61 pubmed publisher
He J, Xia M, Tsang W, Chow K, Xia J. ICA1L forms BAR-domain complexes with PICK1 and is crucial for acrosome formation in spermiogenesis. J Cell Sci. 2015;128:3822-36 pubmed publisher
Wang Y, Zhou L, Li Y, Wang Z, Li Y, Zhang Y, et al. Protein Interacting with C-Kinase 1 Deficiency Impairs Glutathione Synthesis and Increases Oxidative Stress via Reduction of Surface Excitatory Amino Acid Carrier 1. J Neurosci. 2015;35:6429-43 pubmed publisher
Williams K, Balsor J, Beshara S, Beston B, Jones D, Murphy K. Experience-dependent central vision deficits: Neurobiology and visual acuity. Vision Res. 2015;114:68-78 pubmed publisher
Pandey S, Rai R, Gaur P, Prasad S. Development- and age-related alterations in the expression of AMPA receptor subunit GluR2 and its trafficking proteins in the hippocampus of male mouse brain. Biogerontology. 2015;16:317-28 pubmed publisher
Li Q, Wang Z, Yao Y, Jin S, Qian M, Li N, et al. Loss of ICA69 potentiates long-lasting hyperalgesia after subcutaneous formalin injection into the mouse hindpaw. Neurochem Res. 2015;40:579-90 pubmed publisher
Rocca D, Hanley J. PICK1 links AMPA receptor stimulation to Cdc42. Neurosci Lett. 2015;585:155-9 pubmed publisher
Wang Z, Wang Y, Sun C, Yang D, Su L, Xie Y, et al. C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKC? complex and cerebellar plasticity. PLoS ONE. 2013;8:e83862 pubmed publisher
Anggono V, Koc Schmitz Y, Widagdo J, Kormann J, Quan A, Chen C, et al. PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression. Proc Natl Acad Sci U S A. 2013;110:13976-81 pubmed publisher
Jaafari N, Henley J, Hanley J. PICK1 mediates transient synaptic expression of GluA2-lacking AMPA receptors during glycine-induced AMPA receptor trafficking. J Neurosci. 2012;32:11618-30 pubmed publisher
Murphy K, Tcharnaia L, Beshara S, Jones D. Cortical development of AMPA receptor trafficking proteins. Front Mol Neurosci. 2012;5:65 pubmed publisher
Wilke S, Hall B, Antonios J, DeNardo L, Otto S, Yuan B, et al. NeuroD2 regulates the development of hippocampal mossy fiber synapses. Neural Dev. 2012;7:9 pubmed publisher
Ghasemzadeh M, Vasudevan P, Giles C, Purgianto A, Seubert C, Mantsch J. Glutamatergic plasticity in medial prefrontal cortex and ventral tegmental area following extended-access cocaine self-administration. Brain Res. 2011;1413:60-71 pubmed publisher
Zhang J, Wang Y, Chi Z, Keuss M, Pai Y, Kang H, et al. The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior. Cell. 2011;145:284-99 pubmed publisher
Hadlock G, Nelson C, Baucum A, Hanson G, Fleckenstein A. Ex vivo identification of protein-protein interactions involving the dopamine transporter. J Neurosci Methods. 2011;196:303-7 pubmed publisher
Nakamura Y, Wood C, Patton A, Jaafari N, Henley J, Mellor J, et al. PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity. EMBO J. 2011;30:719-30 pubmed publisher
Evers D, MATTA J, HOE H, Zarkowsky D, Lee S, Isaac J, et al. Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation. Nat Neurosci. 2010;13:1199-207 pubmed publisher
Shao X, Zhu L, Wang Y, Lu Y, Wang W, Zhu J, et al. Threonine 82 at the PDZ domain of PICK1 is critical for AMPA receptor interaction and localization. Neurochem Int. 2010;56:962-70 pubmed publisher
Labrie V, Fukumura R, Rastogi A, Fick L, Wang W, Boutros P, et al. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum Mol Genet. 2009;18:3227-43 pubmed publisher
Ghasemzadeh M, Vasudevan P, Mueller C, Seubert C, Mantsch J. Region-specific alterations in glutamate receptor expression and subcellular distribution following extinction of cocaine self-administration. Brain Res. 2009;1267:89-102 pubmed
Ghasemzadeh M, Vasudevan P, Mueller C. Locomotor sensitization to cocaine is associated with distinct pattern of glutamate receptor trafficking to the postsynaptic density in prefrontal cortex: early versus late withdrawal effects. Pharmacol Biochem Behav. 2009;92:383-92 pubmed publisher
Ghasemzadeh M, Mueller C, Vasudevan P. Behavioral sensitization to cocaine is associated with increased glutamate receptor trafficking to the postsynaptic density after extended withdrawal period. Neuroscience. 2009;159:414-26 pubmed publisher
Rocca D, Martin S, Jenkins E, Hanley J. Inhibition of Arp2/3-mediated actin polymerization by PICK1 regulates neuronal morphology and AMPA receptor endocytosis. Nat Cell Biol. 2008;10:259-71 pubmed publisher
product information
TargetType :
Scaffolds
Target :
PICK1
AccessionNum :
Q9NRD5
Clone :
L20/8
HumanGeneName :
PICK1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/L20_8.pdf
IsoType :
IgG2a
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
75-040
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States