product summary
company name :
Neuromab
product type :
antibody
product name :
Pan-Neurofascin
catalog :
75-027
quantity :
100 ug
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
L11A/41
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; loading ...; fig 3d
Alpizar S, BAKER A, Gulledge A, Hoppa M. Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment. Front Cell Neurosci. 2019;13:1 pubmed publisher
Benned Jensen T, Christensen R, Denti F, Perrier J, Rasmussen H, Olesen S. Live Imaging of Kv7.2/7.3 Cell Surface Dynamics at the Axon Initial Segment: High Steady-State Stability and Calpain-Dependent Excitotoxic Downregulation Revealed. J Neurosci. 2016;36:2261-6 pubmed publisher
Jones S, Korobova F, Svitkina T. Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments. J Cell Biol. 2014;205:67-81 pubmed publisher
O Guin K, Gruber R, Raine C, Guzik H, Poulos B, Shafit Zagardo B. Gas6 enhances axonal ensheathment by MBP+ membranous processes in human DRG/OL promyelinating co-cultures. ASN Neuro. 2014;6:e00135 pubmed publisher
Cortes D, Landis M, Ottens A. High-capacity peptide-centric platform to decode the proteomic response to brain injury. Electrophoresis. 2012;33:3712-9 pubmed publisher
Yap C, Vakulenko M, Kruczek K, Motamedi B, Digilio L, Liu J, et al. Doublecortin (DCX) mediates endocytosis of neurofascin independently of microtubule binding. J Neurosci. 2012;32:7439-53 pubmed publisher
Galiano M, Jha S, Ho T, Zhang C, Ogawa Y, Chang K, et al. A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly. Cell. 2012;149:1125-39 pubmed publisher
Dhaunchak A, Becker C, Schulman H, de Faria O, Rajasekharan S, Banwell B, et al. Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis. Ann Neurol. 2012;71:601-13 pubmed publisher
Buffington S, Sobotzik J, Schultz C, Rasband M. I?B? is not required for axon initial segment assembly. Mol Cell Neurosci. 2012;50:1-9 pubmed publisher
Kaphzan H, Buffington S, Jung J, Rasband M, Klann E. Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome. J Neurosci. 2011;31:17637-48 pubmed publisher
Roza C, Castillejo S, Lopez Garcia J. Accumulation of Kv7.2 channels in putative ectopic transduction zones of mice nerve-end neuromas. Mol Pain. 2011;7:58 pubmed publisher
Shi Y, Sun W, McBride J, Cheng J, Shi R. Acrolein induces myelin damage in mammalian spinal cord. J Neurochem. 2011;117:554-64 pubmed publisher
Grubb M, Burrone J. Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability. Nature. 2010;465:1070-4 pubmed publisher
Lorincz A, Nusser Z. Molecular identity of dendritic voltage-gated sodium channels. Science. 2010;328:906-9 pubmed publisher
Ogawa Y, Oses Prieto J, Kim M, Horresh I, Peles E, Burlingame A, et al. ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons. J Neurosci. 2010;30:1038-48 pubmed publisher
Ogawa Y, Rasband M. Proteomic analysis of optic nerve lipid rafts reveals new paranodal proteins. J Neurosci Res. 2009;87:3502-10 pubmed publisher
Lorincz A, Nusser Z. Cell-type-dependent molecular composition of the axon initial segment. J Neurosci. 2008;28:14329-40 pubmed publisher
Hedstrom K, Ogawa Y, Rasband M. AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity. J Cell Biol. 2008;183:635-40 pubmed publisher
Lonigro A, Devaux J. Disruption of neurofascin and gliomedin at nodes of Ranvier precedes demyelination in experimental allergic neuritis. Brain. 2009;132:260-73 pubmed publisher
Micheva K, Smith S. Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits. Neuron. 2007;55:25-36 pubmed
Van Wart A, Trimmer J, Matthews G. Polarized distribution of ion channels within microdomains of the axon initial segment. J Comp Neurol. 2007;500:339-52 pubmed
product information
TargetType :
CAMs
Target :
Pan-Neurofascin
Clone :
L11A/41
HumanGeneName :
----
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/L11A_41.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
ND
Catalog :
75-027
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States