Published Application/Species/Sample/Dilution | Reference |
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- immunohistochemistry - frozen section; mouse; 1:300; fig 8
| Alshammari M, Alshammari T, Laezza F. Improved Methods for Fluorescence Microscopy Detection of Macromolecules at the Axon Initial Segment. Front Cell Neurosci. 2016;10:5 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:1000
| Wimmer V, Harty R, Richards K, Phillips A, Miyazaki H, Nukina N, et al. Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain. J Comp Neurol. 2015;523:814-30 pubmed publisher
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- western blot; mouse; fig 2
| Chang K, Zollinger D, Susuki K, Sherman D, Makara M, Brophy P, et al. Glial ankyrins facilitate paranodal axoglial junction assembly. Nat Neurosci. 2014;17:1673-81 pubmed publisher
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- immunohistochemistry - free floating section; rat; 10 ug/ml
| King A, Manning C, Trimmer J. A unique ion channel clustering domain on the axon initial segment of mammalian neurons. J Comp Neurol. 2014;522:2594-608 pubmed publisher
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| Lujan R, Aguado C, Ciruela F, Arus X, Martín Belmonte A, Alfaro Ruiz R, et al. SK2 Channels Associate With mGlu1α Receptors and CaV2.1 Channels in Purkinje Cells. Front Cell Neurosci. 2018;12:311 pubmed publisher
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| Zhou L, Zhou L, Su L, Cao S, Xie Y, Wang N, et al. Celecoxib Ameliorates Seizure Susceptibility in Autosomal Dominant Lateral Temporal Epilepsy. J Neurosci. 2018;38:3346-3357 pubmed publisher
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| Jones J, Dionne L, Dell Orco J, Parent R, Krueger J, Cheng X, et al. Single amino acid deletion in transmembrane segment D4S6 of sodium channel Scn8a (Nav1.6) in a mouse mutant with a chronic movement disorder. Neurobiol Dis. 2016;89:36-45 pubmed publisher
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| Barbosa C, Tan Z, Wang R, Xie W, Strong J, Patel R, et al. Navβ4 regulates fast resurgent sodium currents and excitability in sensory neurons. Mol Pain. 2015;11:60 pubmed publisher
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| Brügger V, Engler S, Pereira J, Ruff S, Horn M, Welzl H, et al. HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins. PLoS Biol. 2015;13:e1002258 pubmed publisher
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| Hirono M, Ogawa Y, Misono K, Zollinger D, Trimmer J, Rasband M, et al. BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells. J Neurosci. 2015;35:7082-94 pubmed publisher
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| Baalman K, Marin M, Ho T, Godoy M, Cherian L, Robertson C, et al. Axon initial segment-associated microglia. J Neurosci. 2015;35:2283-92 pubmed publisher
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| Xiao M, Bosch M, Nerbonne J, Ornitz D. FGF14 localization and organization of the axon initial segment. Mol Cell Neurosci. 2013;56:393-403 pubmed publisher
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| Ruff C, Ye H, Legasto J, Stribbell N, Wang J, Zhang L, et al. Effects of adult neural precursor-derived myelination on axonal function in the perinatal congenitally dysmyelinated brain: optimizing time of intervention, developing accurate prediction models, and enhancing performance. J Neurosci. 2013;33:11899-915 pubmed publisher
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| Sun W, Wagnon J, Mahaffey C, Briese M, Ule J, Frankel W. Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice. J Physiol. 2013;591:241-55 pubmed publisher
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| Baalman K, Cotton R, Rasband S, Rasband M. Blast wave exposure impairs memory and decreases axon initial segment length. J Neurotrauma. 2013;30:741-51 pubmed publisher
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| Devaux J. Antibodies to gliomedin cause peripheral demyelinating neuropathy and the dismantling of the nodes of Ranvier. Am J Pathol. 2012;181:1402-13 pubmed publisher
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| Buttermore E, Piochon C, Wallace M, Philpot B, Hansel C, Bhat M. Pinceau organization in the cerebellum requires distinct functions of neurofascin in Purkinje and basket neurons during postnatal development. J Neurosci. 2012;32:4724-42 pubmed publisher
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| Duflocq A, Chareyre F, Giovannini M, Couraud F, Davenne M. Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B. BMC Biol. 2011;9:66 pubmed publisher
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| Meehan C, MacDermid V, Montague S, Neuber Hess M, Rose P. Dendrite-derived supernumerary axons on adult axotomized motor neurons possess proteins that are essential for the initiation and propagation of action potentials and synaptic vesicle release. J Neurosci. 2011;31:6732-40 pubmed publisher
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| BINDER E, Rukavina M, Hassani H, Weber M, Nakatani H, Reiff T, et al. Peripheral nervous system progenitors can be reprogrammed to produce myelinating oligodendrocytes and repair brain lesions. J Neurosci. 2011;31:6379-91 pubmed publisher
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| Shepherd M, Pomicter A, Velazco C, Henderson S, Dupree J. Paranodal reorganization results in the depletion of transverse bands in the aged central nervous system. Neurobiol Aging. 2012;33:203.e13-24 pubmed publisher
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| Tong M, Hernandez J, Purcell E, Altschuler R, Duncan R. The intrinsic electrophysiological properties of neurons derived from mouse embryonic stem cells overexpressing neurogenin-1. Am J Physiol Cell Physiol. 2010;299:C1335-44 pubmed publisher
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| Crawford D, Mangiardi M, Song B, Patel R, Du S, Sofroniew M, et al. Oestrogen receptor beta ligand: a novel treatment to enhance endogenous functional remyelination. Brain. 2010;133:2999-3016 pubmed publisher
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| Howell O, Rundle J, Garg A, Komada M, Brophy P, Reynolds R. Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis. J Neuropathol Exp Neurol. 2010;69:1017-1033 pubmed publisher
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| Wimmer V, Reid C, Mitchell S, Richards K, Scaf B, Leaw B, et al. Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus. J Clin Invest. 2010;120:2661-71 pubmed publisher
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| Lorincz A, Nusser Z. Molecular identity of dendritic voltage-gated sodium channels. Science. 2010;328:906-9 pubmed publisher
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| Wimmer V, Reid C, So E, Berkovic S, Petrou S. Axon initial segment dysfunction in epilepsy. J Physiol. 2010;588:1829-40 pubmed publisher
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| Liao Y, Deprez L, Maljevic S, Pitsch J, Claes L, Hristova D, et al. Molecular correlates of age-dependent seizures in an inherited neonatal-infantile epilepsy. Brain. 2010;133:1403-14 pubmed publisher
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| Osorio N, Cathala L, Meisler M, Crest M, Magistretti J, Delmas P. Persistent Nav1.6 current at axon initial segments tunes spike timing of cerebellar granule cells. J Physiol. 2010;588:651-70 pubmed publisher
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| Brackenbury W, Calhoun J, Chen C, Miyazaki H, Nukina N, Oyama F, et al. Functional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth. Proc Natl Acad Sci U S A. 2010;107:2283-8 pubmed publisher
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| Crawford D, Mangiardi M, Xia X, López Valdés H, Tiwari Woodruff S. Functional recovery of callosal axons following demyelination: a critical window. Neuroscience. 2009;164:1407-21 pubmed publisher
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| Sharkey L, Cheng X, Drews V, Buchner D, Jones J, Justice M, et al. The ataxia3 mutation in the N-terminal cytoplasmic domain of sodium channel Na(v)1.6 disrupts intracellular trafficking. J Neurosci. 2009;29:2733-41 pubmed publisher
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| Lorincz A, Nusser Z. Cell-type-dependent molecular composition of the axon initial segment. J Neurosci. 2008;28:14329-40 pubmed publisher
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| O Malley H, Shreiner A, Chen G, Huffnagle G, Isom L. Loss of Na+ channel beta2 subunits is neuroprotective in a mouse model of multiple sclerosis. Mol Cell Neurosci. 2009;40:143-55 pubmed publisher
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| Shakkottai V, Xiao M, Xu L, Wong M, Nerbonne J, Ornitz D, et al. FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons. Neurobiol Dis. 2009;33:81-8 pubmed publisher
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| Mojumder D, Wensel T, Frishman L. Subcellular compartmentalization of two calcium binding proteins, calretinin and calbindin-28 kDa, in ganglion and amacrine cells of the rat retina. Mol Vis. 2008;14:1600-13 pubmed
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| Duflocq A, Le Bras B, Bullier E, Couraud F, Davenne M. Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments. Mol Cell Neurosci. 2008;39:180-92 pubmed publisher
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| Windrem M, Schanz S, Guo M, Tian G, Washco V, Stanwood N, et al. Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse. Cell Stem Cell. 2008;2:553-65 pubmed publisher
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| Mojumder D, Frishman L, Otteson D, Sherry D. Voltage-gated sodium channel alpha-subunits Na(v)1.1, Na(v)1.2, and Na(v)1.6 in the distal mammalian retina. Mol Vis. 2007;13:2163-82 pubmed
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| Lopez Santiago L, Meadows L, Ernst S, Chen C, Malhotra J, McEwen D, et al. Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals. J Mol Cell Cardiol. 2007;43:636-47 pubmed
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| Lopez Santiago L, Pertin M, Morisod X, Chen C, Hong S, Wiley J, et al. Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain. J Neurosci. 2006;26:7984-94 pubmed
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| Rush A, Wittmack E, Tyrrell L, Black J, Dib Hajj S, Waxman S. Differential modulation of sodium channel Na(v)1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily. Eur J Neurosci. 2006;23:2551-62 pubmed
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