product summary
company name :
Neuromab
product type :
antibody
product name :
Shank3
catalog :
73-344
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N367/62
reactivity :
rat
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:100; loading ...; fig 1b
Harony Nicolas H, Kay M, du Hoffmann J, Klein M, Bozdagi Gunal O, Riad M, et al. Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat. elife. 2017;6: pubmed publisher
Ha H, Leal Ortiz S, Lalwani K, Kiyonaka S, Hamachi I, Mysore S, et al. Shank and Zinc Mediate an AMPA Receptor Subunit Switch in Developing Neurons. Front Mol Neurosci. 2018;11:405 pubmed publisher
Drapeau E, Riad M, Kajiwara Y, Buxbaum J. Behavioral Phenotyping of an Improved Mouse Model of Phelan-McDermid Syndrome with a Complete Deletion of the Shank3 Gene. Eneuro. 2018;5: pubmed publisher
Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed publisher
Zhou Y, Kaiser T, Monteiro P, Zhang X, Van der Goes M, Wang D, et al. Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects. Neuron. 2016;89:147-62 pubmed publisher
MacGillavry H, Kerr J, Kassner J, Frost N, Blanpied T. Shank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapses. Eur J Neurosci. 2016;43:179-93 pubmed publisher
Berg J, Lee C, Chen L, Galvan L, Cepeda C, Chen J, et al. JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. Neuron. 2015;88:1173-1191 pubmed publisher
Duffney L, Wei J, Cheng J, Liu W, Smith K, Kittler J, et al. Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism. J Neurosci. 2013;33:15767-78 pubmed publisher
product information
TargetType :
Scaffolds
Target :
Shank3
AccessionNum :
Q9JLU4
Clone :
N367/62
HumanGeneName :
SHANK3
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N367_62.pdf
IsoType :
IgG2a
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-344
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States