product summary
company name :
Neuromab
product type :
antibody
product name :
Arl13b
catalog :
73-287
quantity :
5 ml
price :
319 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N295B/66
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, western blot knockout validation
more info or order :
citations: 29
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:200; loading ...; fig 6
  • immunocytochemistry; mouse; 1:200; loading ...; fig 4
Hua K, Ferland R. Fixation methods can differentially affect ciliary protein immunolabeling. Cilia. 2017;6:5 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 5c
Badgandi H, Hwang S, Shimada I, Loriot E, Mukhopadhyay S. Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins. J Cell Biol. 2017;216:743-760 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 4b
Di Pietro C, Marazziti D, La Sala G, Abbaszadeh Z, Golini E, Matteoni R, et al. Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma. Cell Mol Neurobiol. 2017;37:145-154 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 6
Guen V, Gamble C, Perez D, Bourassa S, Zappel H, Gartner J, et al. STAR syndrome-associated CDK10/Cyclin M regulates actin network architecture and ciliogenesis. Cell Cycle. 2016;15:678-88 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5a
Liu Y, Snedecor E, Choi Y, Yang N, Zhang X, Xu Y, et al. Gorab Is Required for Dermal Condensate Cells to Respond to Hedgehog Signals during Hair Follicle Morphogenesis. J Invest Dermatol. 2016;136:378-386 pubmed publisher
  • immunocytochemistry; human; 1:200
Kowal T, Falk M. Primary cilia found on HeLa and other cancer cells. Cell Biol Int. 2015;39:1341-7 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig s7a
Yang N, Li L, Eguether T, Sundberg J, Pazour G, Chen J. Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis. Development. 2015;142:2194-202 pubmed publisher
Engelke M, Waas B, Kearns S, Suber A, Boss A, Allen B, et al. Acute Inhibition of Heterotrimeric Kinesin-2 Function Reveals Mechanisms of Intraflagellar Transport in Mammalian Cilia. Curr Biol. 2019;: pubmed publisher
Gadadhar S, Dadi H, Bodakuntla S, Schnitzler A, Bièche I, Rusconi F, et al. Tubulin glycylation controls primary cilia length. J Cell Biol. 2017;216:2701-2713 pubmed publisher
Monis W, Faundez V, Pazour G. BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia. J Cell Biol. 2017;216:2131-2150 pubmed publisher
Pal K, Hwang S, Somatilaka B, Badgandi H, Jackson P, DeFea K, et al. Smoothened determines ?-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. J Cell Biol. 2016;212:861-75 pubmed publisher
Bhattacharyya S, Rainey M, Arya P, Mohapatra B, Mushtaq I, Dutta S, et al. Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016;6:20727 pubmed publisher
Stewart K, Gaitan Y, Shafer M, Aoudjit L, Hu D, Sharma R, et al. A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects. PLoS Genet. 2016;12:e1005785 pubmed publisher
Yao P, Petralia R, Ott C, Wang Y, Lippincott Schwartz J, Mattson M. Dendrosomatic Sonic Hedgehog Signaling in Hippocampal Neurons Regulates Axon Elongation. J Neurosci. 2015;35:16126-41 pubmed publisher
Endicott S, Basu B, Khokha M, Brueckner M. The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry. Development. 2015;142:4068-79 pubmed publisher
Joiner A, Green W, McIntyre J, Allen B, Schwob J, Martens J. Primary Cilia on Horizontal Basal Cells Regulate Regeneration of the Olfactory Epithelium. J Neurosci. 2015;35:13761-72 pubmed publisher
Garcia Gonzalo F, Phua S, Roberson E, Garcia G, Abedin M, Schurmans S, et al. Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling. Dev Cell. 2015;34:400-409 pubmed publisher
Laclef C, Anselme I, Besse L, Catala M, Palmyre A, Baas D, et al. The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor. Hum Mol Genet. 2015;24:4997-5014 pubmed publisher
Omori Y, Chaya T, Yoshida S, Irie S, Tsujii T, Furukawa T. Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control. PLoS ONE. 2015;10:e0128422 pubmed publisher
Chang R, Petersen J, Niswander L, Liu A. A hypomorphic allele reveals an important role of inturned in mouse skeletal development. Dev Dyn. 2015;244:736-47 pubmed publisher
Banda E, McKinsey A, Germain N, Carter J, Anderson N, Grabel L. Cell polarity and neurogenesis in embryonic stem cell-derived neural rosettes. Stem Cells Dev. 2015;24:1022-33 pubmed publisher
Chen J, Laclef C, Moncayo A, Snedecor E, Yang N, Li L, et al. The ciliopathy gene Rpgrip1l is essential for hair follicle development. J Invest Dermatol. 2015;135:701-709 pubmed publisher
Menzl I, LeBeau L, Pandey R, Hassounah N, Li F, Nagle R, et al. Loss of primary cilia occurs early in breast cancer development. Cilia. 2014;3:7 pubmed publisher
Ruppersburg C, Hartzell H. The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesis. Mol Biol Cell. 2014;25:1793-807 pubmed publisher
Tuz K, Bachmann Gagescu R, O Day D, Hua K, Isabella C, Phelps I, et al. Mutations in CSPP1 cause primary cilia abnormalities and Joubert syndrome with or without Jeune asphyxiating thoracic dystrophy. Am J Hum Genet. 2014;94:62-72 pubmed publisher
Hollingsworth T, Gross A. The severe autosomal dominant retinitis pigmentosa rhodopsin mutant Ter349Glu mislocalizes and induces rapid rod cell death. J Biol Chem. 2013;288:29047-55 pubmed publisher
Hassounah N, Nagle R, Saboda K, Roe D, Dalkin B, McDermott K. Primary cilia are lost in preinvasive and invasive prostate cancer. PLoS ONE. 2013;8:e68521 pubmed publisher
Piotrowska Nitsche K, Caspary T. Live imaging of individual cell divisions in mouse neuroepithelium shows asymmetry in cilium formation and Sonic hedgehog response. Cilia. 2012;1: pubmed publisher
Heydet D, Chen L, Larter C, Inglis C, Silverman M, Farrell G, et al. A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice. Dev Neurobiol. 2013;73:1-13 pubmed publisher
product information
TargetType :
Rare Disease
Target :
Arl13b
AccessionNum :
Q640N2
Clone :
N295B/66
HumanGeneName :
ARL13B
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N295B_66.pdf
IsoType :
IgG2a
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-287
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States