product summary
company name :
Neuromab
product type :
antibody
product name :
ASIC1
catalog :
73-277
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N271/44
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
citations: 5
Reference
Farrag M, Drobish J, Puhl H, Kim J, Herold P, Kaufman M, et al. Endomorphins potentiate acid-sensing ion channel currents and enhance the lactic acid-mediated increase in arterial blood pressure: effects amplified in hindlimb ischaemia. J Physiol. 2017;595:7167-7183 pubmed publisher
Chen B, Liu J, Ho T, Ding X, Mo Y. ERK-mediated NF-?B activation through ASIC1 in response to acidosis. Oncogenesis. 2016;5:e279 pubmed publisher
Lin S, Sun W, Chen C. Genetic exploration of the role of acid-sensing ion channels. Neuropharmacology. 2015;94:99-118 pubmed publisher
Vig P, Hearst S, Shao Q, Lopez M. Knockdown of acid-sensing ion channel 1a (ASIC1a) suppresses disease phenotype in SCA1 mouse model. Cerebellum. 2014;13:479-90 pubmed publisher
Diochot S, Baron A, Salinas M, Douguet D, Scarzello S, Dabert Gay A, et al. Black mamba venom peptides target acid-sensing ion channels to abolish pain. Nature. 2012;490:552-5 pubmed publisher
product information
TargetType :
Ion channels
Target :
ASIC1
AccessionNum :
Q6NXK8
Clone :
N271/44
HumanGeneName :
ASIC1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N271_44.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-277
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States