product summary
company name :
Neuromab
product type :
antibody
product name :
TrpV1
catalog :
73-254
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N221/17
reactivity :
rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry knockout validation
more info or order :
citations: 8
Reference
Gu Y, Jukkola P, Wang Q, Esparza T, Zhao Y, Brody D, et al. Polarity of varicosity initiation in central neuron mechanosensation. J Cell Biol. 2017;216:2179-2199 pubmed publisher
Cohen M, Johnson W, Pilat J, Kiselar J, DeFrancesco Lisowitz A, Zigmond R, et al. Nerve Growth Factor Regulates Transient Receptor Potential Vanilloid 2 via Extracellular Signal-Regulated Kinase Signaling To Enhance Neurite Outgrowth in Developing Neurons. Mol Cell Biol. 2015;35:4238-52 pubmed publisher
Mickle A, Shepherd A, Loo L, Mohapatra D. Induction of thermal and mechanical hypersensitivity by parathyroid hormone-related peptide through upregulation of TRPV1 function and trafficking. Pain. 2015;156:1620-36 pubmed publisher
Iannotti F, Hill C, Leo A, Alhusaini A, Soubrane C, Mazzarella E, et al. Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability. ACS Chem Neurosci. 2014;5:1131-41 pubmed publisher
Ambrosino P, Soldovieri M, De Maria M, Russo C, Taglialatela M. Functional and biochemical interaction between PPAR? receptors and TRPV1 channels: Potential role in PPAR? agonists-mediated analgesia. Pharmacol Res. 2014;87:113-22 pubmed publisher
Navarria A, Tamburella A, Iannotti F, Micale V, Camillieri G, Gozzo L, et al. The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis. Pharmacol Res. 2014;87:151-9 pubmed publisher
Bouyer P, Tang X, Weber C, Shen L, Turner J, Matthews J. Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. Am J Physiol Gastrointest Liver Physiol. 2013;304:G142-56 pubmed publisher
Loo L, Shepherd A, Mickle A, Lorca R, Shutov L, Usachev Y, et al. The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical G??-dependent modulation of TRPV1 channel. J Neurosci. 2012;32:11942-55 pubmed publisher
product information
TargetType :
Trp channels
Target :
TrpV1
AccessionNum :
O35433
Clone :
N221/17
HumanGeneName :
TRPV1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N221_17.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-254
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States