product summary
company name :
Neuromab
product type :
antibody
product name :
SynCAM4
catalog :
73-247
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N244/5
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse
Chang K, Zollinger D, Susuki K, Sherman D, Makara M, Brophy P, et al. Glial ankyrins facilitate paranodal axoglial junction assembly. Nat Neurosci. 2014;17:1673-81 pubmed publisher
Bang M, Vainshtein A, Yang H, Eshed Eisenbach Y, Devaux J, Werner H, et al. Glial M6B stabilizes the axonal membrane at peripheral nodes of Ranvier. Glia. 2018;66:801-812 pubmed publisher
Yamana S, Tokiyama A, Mizutani K, Hirata K, Takai Y, Rikitake Y. The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation. PLoS ONE. 2015;10:e0124259 pubmed publisher
Minis A, Dahary D, Manor O, Leshkowitz D, Pilpel Y, Yaron A. Subcellular transcriptomics-dissection of the mRNA composition in the axonal compartment of sensory neurons. Dev Neurobiol. 2014;74:365-81 pubmed publisher
Golan N, Kartvelishvily E, Spiegel I, Salomon D, Sabanay H, Rechav K, et al. Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy. J Neurosci. 2013;33:10950-61 pubmed publisher
Zhu Y, Li H, Li K, Zhao X, An T, Hu X, et al. Necl-4/SynCAM-4 is expressed in myelinating oligodendrocytes but not required for axonal myelination. PLoS ONE. 2013;8:e64264 pubmed publisher
Rehak R, Bartoletti T, Engbers J, Berecki G, Turner R, Zamponi G. Low voltage activation of KCa1.1 current by Cav3-KCa1.1 complexes. PLoS ONE. 2013;8:e61844 pubmed publisher
Sugiyama H, Mizutani K, Kurita S, Okimoto N, Shimono Y, Takai Y. Interaction of Necl-4/CADM4 with ErbB3 and integrin ?6 ?4 and inhibition of ErbB2/ErbB3 signaling and hemidesmosome disassembly. Genes Cells. 2013;18:519-28 pubmed publisher
Susuki K, Raphael A, Ogawa Y, Stankewich M, Peles E, Talbot W, et al. Schwann cell spectrins modulate peripheral nerve myelination. Proc Natl Acad Sci U S A. 2011;108:8009-14 pubmed publisher
product information
TargetType :
CAMs
Target :
SynCAM4
AccessionNum :
Q8R464
Clone :
N244/5
HumanGeneName :
CADM4
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N244_5.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-247
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States