product summary
company name :
Neuromab
product type :
antibody
product name :
Cav3.1 Ca2+ channel
catalog :
73-206
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N178A/9
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
citations: 7
Reference
Stoyas C, Bushart D, Switonski P, Ward J, Alaghatta A, Tang M, et al. Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7. Neuron. 2019;: pubmed publisher
Vierra N, Kirmiz M, van der List D, Santana L, Trimmer J. Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons. elife. 2019;8: pubmed publisher
Devergnas A, Chen E, Ma Y, Hamada I, Pittard D, Kammermeier S, et al. Anatomical localization of Cav3.1 calcium channels and electrophysiological effects of T-type calcium channel blockade in the motor thalamus of MPTP-treated monkeys. J Neurophysiol. 2016;115:470-85 pubmed publisher
Curran J, Musa H, Kline C, Makara M, Little S, Higgins J, et al. Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria. J Biol Chem. 2015;290:12210-21 pubmed publisher
Puthussery T, Venkataramani S, Gayet Primo J, Smith R, Taylor W. NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina. J Neurosci. 2013;33:16045-59 pubmed publisher
Valerie N, Dziegielewska B, Hosing A, Augustin E, Gray L, Brautigan D, et al. Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells. Biochem Pharmacol. 2013;85:888-97 pubmed publisher
Goonasekera S, Hammer K, Auger Messier M, Bodi I, Chen X, Zhang H, et al. Decreased cardiac L-type Ca²? channel activity induces hypertrophy and heart failure in mice. J Clin Invest. 2012;122:280-90 pubmed publisher
product information
TargetType :
Ca2+ channels
Target :
Cav3.1 Ca2+ channel
AccessionNum :
Q9WUT2
Clone :
N178A/9
HumanGeneName :
CACNA1G
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N178A_9.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-206
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States