product summary
company name :
Neuromab
product type :
antibody
product name :
GABA(B)R1
catalog :
73-183
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N93A/49
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, western blot knockout validation
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; 1:15
Karls A, Mynlieff M. GABA(B) receptors couple to Gαq to mediate increases in voltage-dependent calcium current during development. J Neurochem. 2015;135:88-100 pubmed publisher
  • immunoprecipitation; mouse; loading ...; fig 2i
  • western blot; mouse; loading ...; fig 2a
Terunuma M, Revilla Sanchez R, Quadros I, Deng Q, Deeb T, Lumb M, et al. Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory. J Neurosci. 2014;34:804-16 pubmed publisher
Zemoura K, Balakrishnan K, Grampp T, Benke D. Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII) β-Dependent Phosphorylation of GABAB1 Triggers Lysosomal Degradation of GABAB Receptors via Mind Bomb-2 (MIB2)-Mediated Lys-63-Linked Ubiquitination. Mol Neurobiol. 2019;56:1293-1309 pubmed publisher
Wright R, Newey S, Ilie A, Wefelmeyer W, Raimondo J, Ginham R, et al. Neuronal Chloride Regulation via KCC2 Is Modulated through a GABAB Receptor Protein Complex. J Neurosci. 2017;37:5447-5462 pubmed publisher
Schwenk J, Pérez Garci E, Schneider A, Kollewe A, Gauthier Kemper A, Fritzius T, et al. Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics. Nat Neurosci. 2016;19:233-42 pubmed publisher
Frederikse P, Kasinathan C. KCC2 expression supersedes NKCC1 in mature fiber cells in mouse and rabbit lenses. Mol Vis. 2015;21:1142-50 pubmed
Frederikse P, Nandanoor A, Kasinathan C. Fragile X Syndrome FMRP Co-localizes with Regulatory Targets PSD-95, GABA Receptors, CaMKIIα, and mGluR5 at Fiber Cell Membranes in the Eye Lens. Neurochem Res. 2015;40:2167-76 pubmed publisher
Kramer A, Ingraham N, Sharpe E, Mynlieff M. Levels of Ca(V)1.2 L-Type Ca(2+) Channels Peak in the First Two Weeks in Rat Hippocampus Whereas Ca(V)1.3 Channels Steadily Increase through Development. J Signal Transduct. 2012;2012:597214 pubmed publisher
Padgett C, Lalive A, Tan K, Terunuma M, Munoz M, Pangalos M, et al. Methamphetamine-evoked depression of GABA(B) receptor signaling in GABA neurons of the VTA. Neuron. 2012;73:978-89 pubmed publisher
Schwindinger W, Mirshahi U, Baylor K, Sheridan K, Stauffer A, Usefof S, et al. Synergistic roles for G-protein ?3 and ?7 subtypes in seizure susceptibility as revealed in double knock-out mice. J Biol Chem. 2012;287:7121-33 pubmed publisher
Pacey L, Tharmalingam S, Hampson D. Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome. J Pharmacol Exp Ther. 2011;338:897-905 pubmed publisher
Broussard D, Titley H, Antflick J, Hampson D. Motor learning in the VOR: the cerebellar component. Exp Brain Res. 2011;210:451-63 pubmed publisher
Pacey L, Doss L, Cifelli C, van der Kooy D, Heximer S, Hampson D. Genetic deletion of regulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1 knockout mouse. Mol Cell Neurosci. 2011;46:563-72 pubmed publisher
product information
TargetType :
Receptors
Target :
GABA(B)R1
AccessionNum :
Q9Z0U4
Clone :
N93A/49
HumanGeneName :
GABBR1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N93A_49.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-183
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States