product summary
company name :
Neuromab
product type :
antibody
product name :
GABA(B)R2
catalog :
73-124
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N81/2
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
citations: 10
Reference
Workman E, Haddick P, Bush K, Dilly G, Niere F, Zemelman B, et al. Rapid antidepressants stimulate the decoupling of GABA(B) receptors from GIRK/Kir3 channels through increased protein stability of 14-3-3η. Mol Psychiatry. 2015;20:298-310 pubmed publisher
Murthy R, Kim J, Sun X, Giger R, Fink D, Mata M. Post-transcriptional regulation of GABAB receptor and GIRK1 channels by Nogo receptor 1. Mol Brain. 2013;6:30 pubmed publisher
Nguyen M, Du F, Felice C, Shan X, Nigam A, Mandel G, et al. MeCP2 is critical for maintaining mature neuronal networks and global brain anatomy during late stages of postnatal brain development and in the mature adult brain. J Neurosci. 2012;32:10021-34 pubmed publisher
Maity B, Stewart A, Yang J, Loo L, Sheff D, Shepherd A, et al. Regulator of G protein signaling 6 (RGS6) protein ensures coordination of motor movement by modulating GABAB receptor signaling. J Biol Chem. 2012;287:4972-81 pubmed publisher
Paris Robidas S, Brochu E, Sintes M, Emond V, Bousquet M, Vandal M, et al. Defective dentate nucleus GABA receptors in essential tremor. Brain. 2012;135:105-16 pubmed publisher
Lodewyks C, Rodriguez J, Yan J, Lerner B, Lipschitz J, Nfon C, et al. GABA-B receptor activation inhibits the in vitro migration of malignant hepatocytes. Can J Physiol Pharmacol. 2011;89:393-400 pubmed publisher
Pacey L, Tharmalingam S, Hampson D. Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome. J Pharmacol Exp Ther. 2011;338:897-905 pubmed publisher
Broussard D, Titley H, Antflick J, Hampson D. Motor learning in the VOR: the cerebellar component. Exp Brain Res. 2011;210:451-63 pubmed publisher
Pacey L, Doss L, Cifelli C, van der Kooy D, Heximer S, Hampson D. Genetic deletion of regulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1 knockout mouse. Mol Cell Neurosci. 2011;46:563-72 pubmed publisher
Nassirpour R, Bahima L, Lalive A, Lüscher C, Lujan R, Slesinger P. Morphine- and CaMKII-dependent enhancement of GIRK channel signaling in hippocampal neurons. J Neurosci. 2010;30:13419-30 pubmed publisher
product information
TargetType :
Receptors
Target :
GABA(B)R2
AccessionNum :
O75899
Clone :
N81/2
HumanGeneName :
GABBR2
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N81_2.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-124
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States