product summary
company name :
Neuromab
product type :
antibody
product name :
HCN1
catalog :
73-110
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N70/28
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:50; fig s1
Kupferman J, Basu J, Russo M, Guevarra J, Cheung S, Siegelbaum S. Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment. Cell. 2014;158:1335-1347 pubmed publisher
Gessele N, Garcia Pino E, Omerbasic D, Park T, Koch U. Structural Changes and Lack of HCN1 Channels in the Binaural Auditory Brainstem of the Naked Mole-Rat (Heterocephalus glaber). PLoS ONE. 2016;11:e0146428 pubmed publisher
Hellmer C, Zhou Y, Fyk Kolodziej B, Hu Z, Ichinose T. Morphological and physiological analysis of type-5 and other bipolar cells in the Mouse Retina. Neuroscience. 2016;315:246-58 pubmed publisher
Farshi P, Fyk Kolodziej B, Krolewski D, Walker P, Ichinose T. Dopamine D1 receptor expression is bipolar cell type-specific in the mouse retina. J Comp Neurol. 2016;524:2059-79 pubmed publisher
Masri R, Percival K, Koizumi A, Martin P, Grünert U. Connectivity between the OFF bipolar type DB3a and six types of ganglion cell in the marmoset retina. J Comp Neurol. 2016;524:1839-58 pubmed publisher
Kole M, Qian J, Waase M, Klassen T, Chen T, Augustine G, et al. Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. J Neurosci. 2015;35:11433-44 pubmed publisher
Zhang Y, Bonnan A, Bony G, Ferezou I, Pietropaolo S, Ginger M, et al. Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1(-/y) mice. Nat Neurosci. 2014;17:1701-9 pubmed publisher
Weltzien F, Percival K, Martin P, Grünert U. Analysis of bipolar and amacrine populations in marmoset retina. J Comp Neurol. 2015;523:313-34 pubmed publisher
Liu Q, Manis P, Davis R. I h and HCN channels in murine spiral ganglion neurons: tonotopic variation, local heterogeneity, and kinetic model. J Assoc Res Otolaryngol. 2014;15:585-99 pubmed publisher
Pan Y, Bhattarai S, Modestou M, Drack A, Chetkovich D, Baker S. TRIP8b is required for maximal expression of HCN1 in the mouse retina. PLoS ONE. 2014;9:e85850 pubmed publisher
Puthussery T, Venkataramani S, Gayet Primo J, Smith R, Taylor W. NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina. J Neurosci. 2013;33:16045-59 pubmed publisher
Rinaldi A, Defterali C, Mialot A, Garden D, Beraneck M, Nolan M. HCN1 channels in cerebellar Purkinje cells promote late stages of learning and constrain synaptic inhibition. J Physiol. 2013;591:5691-709 pubmed publisher
Brewster A, Lugo J, Patil V, Lee W, Qian Y, Vanegas F, et al. Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage. PLoS ONE. 2013;8:e57808 pubmed publisher
Bonin R, Zurek A, Yu J, Bayliss D, Orser B. Hyperpolarization-activated current (In) is reduced in hippocampal neurons from Gabra5-/- mice. PLoS ONE. 2013;8:e58679 pubmed publisher
Abbas S, Hamade K, Yang E, Nawy S, Smith R, Pettit D. Directional summation in non-direction selective retinal ganglion cells. PLoS Comput Biol. 2013;9:e1002969 pubmed publisher
Huang Z, Lujan R, Martínez Hernández J, Lewis A, Chetkovich D, Shah M. TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels. J Neurosci. 2012;32:14835-48 pubmed publisher
Ying S, Kanda V, Hu Z, Purtell K, King E, Abbott G, et al. Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits. PLoS ONE. 2012;7:e42756 pubmed publisher
Almanza A, Luis E, Mercado F, Vega R, Soto E. Molecular identity, ontogeny, and cAMP modulation of the hyperpolarization-activated current in vestibular ganglion neurons. J Neurophysiol. 2012;108:2264-75 pubmed publisher
Kanyshkova T, Meuth P, Bista P, Liu Z, Ehling P, Caputi L, et al. Differential regulation of HCN channel isoform expression in thalamic neurons of epileptic and non-epileptic rat strains. Neurobiol Dis. 2012;45:450-61 pubmed publisher
Anderson W, Galvan E, Mauna J, Thiels E, Barrionuevo G. Properties and functional implications of I (h) in hippocampal area CA3 interneurons. Pflugers Arch. 2011;462:895-912 pubmed publisher
McClelland S, Flynn C, Dube C, Richichi C, Zha Q, Ghestem A, et al. Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy. Ann Neurol. 2011;70:454-64 pubmed publisher
Piskorowski R, Santoro B, Siegelbaum S. TRIP8b splice forms act in concert to regulate the localization and expression of HCN1 channels in CA1 pyramidal neurons. Neuron. 2011;70:495-509 pubmed publisher
Huang Z, Lujan R, Kadurin I, Uebele V, Renger J, Dolphin A, et al. Presynaptic HCN1 channels regulate Cav3.2 activity and neurotransmission at select cortical synapses. Nat Neurosci. 2011;14:478-86 pubmed publisher
Giesbrecht C, Mackay J, Silveira H, Urban J, Colmers W. Countervailing modulation of Ih by neuropeptide Y and corticotrophin-releasing factor in basolateral amygdala as a possible mechanism for their effects on stress-related behaviors. J Neurosci. 2010;30:16970-82 pubmed publisher
Li Y, Serwanski D, Miralles C, Fiondella C, LoTurco J, Rubio M, et al. Synaptic and nonsynaptic localization of protocadherin-gammaC5 in the rat brain. J Comp Neurol. 2010;518:3439-63 pubmed publisher
Noam Y, Zha Q, Phan L, Wu R, Chetkovich D, Wadman W, et al. Trafficking and surface expression of hyperpolarization-activated cyclic nucleotide-gated channels in hippocampal neurons. J Biol Chem. 2010;285:14724-36 pubmed publisher
Hegle A, Nazzari H, Roth A, Angoli D, Accili E. Evolutionary emergence of N-glycosylation as a variable promoter of HCN channel surface expression. Am J Physiol Cell Physiol. 2010;298:C1066-76 pubmed publisher
Arimitsu T, Nuriya M, Ikeda K, Takahashi T, Yasui M. Activity-dependent regulation of HCN1 protein in cortical neurons. Biochem Biophys Res Commun. 2009;387:87-91 pubmed publisher
product information
TargetType :
Ion channels
Target :
HCN1
AccessionNum :
Q9JKB0
Clone :
N70/28
HumanGeneName :
HCN1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N70_28.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-110
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States