product summary
company name :
Neuromab
product type :
antibody
product name :
FGF14/FHF4
catalog :
73-096
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N56/21
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry
more info or order :
citations: 13
Reference
Bosch M, Nerbonne J, Townsend R, Miyazaki H, Nukina N, Ornitz D, et al. Proteomic analysis of native cerebellar iFGF14 complexes. Channels (Austin). 2016;10:297-312 pubmed publisher
Bosch M, Carrasquillo Y, Ransdell J, Kanakamedala A, Ornitz D, Nerbonne J. Intracellular FGF14 (iFGF14) Is Required for Spontaneous and Evoked Firing in Cerebellar Purkinje Neurons and for Motor Coordination and Balance. J Neurosci. 2015;35:6752-69 pubmed publisher
Baalman K, Marin M, Ho T, Godoy M, Cherian L, Robertson C, et al. Axon initial segment-associated microglia. J Neurosci. 2015;35:2283-92 pubmed publisher
Yan H, Pablo J, Wang C, Pitt G. FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neurons. elife. 2014;3:e04193 pubmed publisher
Bosch M, Nerbonne J, Ornitz D. Dual transgene expression in murine cerebellar Purkinje neurons by viral transduction in vivo. PLoS ONE. 2014;9:e104062 pubmed publisher
Puthussery T, Venkataramani S, Gayet Primo J, Smith R, Taylor W. NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina. J Neurosci. 2013;33:16045-59 pubmed publisher
Xiao M, Bosch M, Nerbonne J, Ornitz D. FGF14 localization and organization of the axon initial segment. Mol Cell Neurosci. 2013;56:393-403 pubmed publisher
Yan H, Pablo J, Pitt G. FGF14 regulates presynaptic Ca2+ channels and synaptic transmission. Cell Rep. 2013;4:66-75 pubmed publisher
Kaphzan H, Buffington S, Jung J, Rasband M, Klann E. Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome. J Neurosci. 2011;31:17637-48 pubmed publisher
Grubb M, Burrone J. Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability. Nature. 2010;465:1070-4 pubmed publisher
Diwakar S, Magistretti J, Goldfarb M, Naldi G, D Angelo E. Axonal Na+ channels ensure fast spike activation and back-propagation in cerebellar granule cells. J Neurophysiol. 2009;101:519-32 pubmed publisher
Shakkottai V, Xiao M, Xu L, Wong M, Nerbonne J, Ornitz D, et al. FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons. Neurobiol Dis. 2009;33:81-8 pubmed publisher
Laezza F, Gerber B, Lou J, Kozel M, Hartman H, Craig A, et al. The FGF14(F145S) mutation disrupts the interaction of FGF14 with voltage-gated Na+ channels and impairs neuronal excitability. J Neurosci. 2007;27:12033-44 pubmed
product information
TargetType :
Other
Target :
FGF14/FHF4
AccessionNum :
O89096
Clone :
N56/21
HumanGeneName :
FGF14
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N56_21.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Fail
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-096
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States