product summary
company name :
Neuromab
product type :
antibody
product name :
Pan-Shank
catalog :
73-089
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N23B/49
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 29
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 1d
Zhang N, Zhong P, Shin S, Metallo J, Danielson E, Olsen C, et al. S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model. J Neurosci. 2015;35:1892-904 pubmed publisher
  • western blot; mouse; fig 3
Serrano F, Tapia Rojas C, Carvajal F, Hancke J, Cerpa W, Inestrosa N. Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice. Mol Neurodegener. 2014;9:61 pubmed publisher
  • immunohistochemistry; mouse
Tao Cheng J, Thein S, Yang Y, Reese T, Gallant P. Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation. Neuroscience. 2014;266:80-90 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:400
  • western blot; mouse; 1:1000
Hoy J, Haeger P, Constable J, Arias R, McCallum R, Kyweriga M, et al. Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions. J Neurosci. 2013;33:9364-84 pubmed publisher
Lee N, Song J, Cho H, Sung Y, Lee T, Chung A, et al. Hexa (ethylene glycol) derivative of benzothiazole aniline promotes dendritic spine formation through the RasGRF1-Ras dependent pathway. Biochim Biophys Acta. 2016;1862:284-95 pubmed publisher
MacGillavry H, Kerr J, Kassner J, Frost N, Blanpied T. Shank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapses. Eur J Neurosci. 2016;43:179-93 pubmed publisher
Pinheiro S, Silva J, Mota C, Vaz Silva J, Veloso A, Pinto V, et al. Tau Mislocation in Glucocorticoid-Triggered Hippocampal Pathology. Mol Neurobiol. 2016;53:4745-53 pubmed publisher
Stanic J, Carta M, Eberini I, Pelucchi S, Marcello E, Genazzani A, et al. Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex. Nat Commun. 2015;6:10181 pubmed publisher
Gill I, Droubi S, Giovedi S, Fedder K, Bury L, Bosco F, et al. Presynaptic NMDA receptors - dynamics and distribution in developing axons in vitro and in vivo. J Cell Sci. 2015;128:768-80 pubmed publisher
de Andrade G, Kunzelman L, Merrill M, Fuerst P. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. Mol Vis. 2014;20:1422-33 pubmed
Tao Cheng J, Yang Y, Bayer K, Reese T, Dosemeci A. NMDA-induced accumulation of Shank at the postsynaptic density is mediated by CaMKII. Biochem Biophys Res Commun. 2014;450:808-11 pubmed publisher
Lugo J, Smith G, Arbuckle E, White J, Holley A, Floruta C, et al. Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins. Front Mol Neurosci. 2014;7:27 pubmed publisher
Lussier M, Gu X, Lu W, Roche K. Casein kinase 2 phosphorylates GluA1 and regulates its surface expression. Eur J Neurosci. 2014;39:1148-58 pubmed publisher
Cheadle L, Biederer T. The novel synaptogenic protein Farp1 links postsynaptic cytoskeletal dynamics and transsynaptic organization. J Cell Biol. 2012;199:985-1001 pubmed publisher
Ricciardi S, Ungaro F, Hambrock M, Rademacher N, Stefanelli G, Brambilla D, et al. CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons. Nat Cell Biol. 2012;14:911-23 pubmed publisher
Hu J, Yang L, Kammermeier P, Moore C, BRAKEMAN P, Tu J, et al. Preso1 dynamically regulates group I metabotropic glutamate receptors. Nat Neurosci. 2012;15:836-44 pubmed publisher
Gardoni F, Saraceno C, Malinverno M, Marcello E, Verpelli C, Sala C, et al. The neuropeptide PACAP38 induces dendritic spine remodeling through ADAM10-N-cadherin signaling pathway. J Cell Sci. 2012;125:1401-6 pubmed publisher
Jarome T, Werner C, Kwapis J, Helmstetter F. Activity dependent protein degradation is critical for the formation and stability of fear memory in the amygdala. PLoS ONE. 2011;6:e24349 pubmed publisher
Fogel A, Stagi M, Perez de Arce K, Biederer T. Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation. EMBO J. 2011;30:4728-38 pubmed publisher
Verpelli C, Dvoretskova E, Vicidomini C, Rossi F, Chiappalone M, Schoen M, et al. Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses. J Biol Chem. 2011;286:34839-50 pubmed publisher
Malinverno M, Carta M, Epis R, Marcello E, Verpelli C, Cattabeni F, et al. Synaptic localization and activity of ADAM10 regulate excitatory synapses through N-cadherin cleavage. J Neurosci. 2010;30:16343-55 pubmed publisher
Marcello E, Epis R, Saraceno C, Gardoni F, Borroni B, Cattabeni F, et al. SAP97-mediated local trafficking is altered in Alzheimer disease patients' hippocampus. Neurobiol Aging. 2012;33:422.e1-10 pubmed publisher
Sharma N, Deppmann C, Harrington A, St Hillaire C, Chen Z, Lee F, et al. Long-distance control of synapse assembly by target-derived NGF. Neuron. 2010;67:422-34 pubmed publisher
Moreau M, Piguel N, Papouin T, Koehl M, Durand C, Rubio M, et al. The planar polarity protein Scribble1 is essential for neuronal plasticity and brain function. J Neurosci. 2010;30:9738-52 pubmed publisher
Tao Cheng J, Dosemeci A, Gallant P, Smith C, Reese T. Activity induced changes in the distribution of Shanks at hippocampal synapses. Neuroscience. 2010;168:11-7 pubmed publisher
Westerholz S, de Lima A, Voigt T. Regulation of early spontaneous network activity and GABAergic neurons development by thyroid hormone. Neuroscience. 2010;168:573-89 pubmed publisher
Perez de Arce K, de Arce K, Varela Nallar L, Farias O, Cifuentes A, Bull P, et al. Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation. J Neurosci. 2010;30:3728-38 pubmed publisher
Zibetti C, Adamo A, Binda C, Forneris F, Toffolo E, Verpelli C, et al. Alternative splicing of the histone demethylase LSD1/KDM1 contributes to the modulation of neurite morphogenesis in the mammalian nervous system. J Neurosci. 2010;30:2521-32 pubmed publisher
Suh Y, Terashima A, Petralia R, Wenthold R, Isaac J, Roche K, et al. A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking. Nat Neurosci. 2010;13:338-43 pubmed publisher
product information
TargetType :
Scaffolds
Target :
Pan-Shank
Clone :
N23B/49
HumanGeneName :
----
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N23B_49.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
ND
Catalog :
73-089
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States