product summary
company name :
Neuromab
product type :
antibody
product name :
SAP102
catalog :
73-058
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N19/2
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 31
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 2d
Koster K, Francesconi W, Berton F, Alahmadi S, Srinivas R, Yoshii A. Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model. elife. 2019;8: pubmed publisher
  • western blot; mouse; loading ...; fig 1f
  • western blot; rat; loading ...; fig 1e
Won S, Incontro S, Nicoll R, Roche K. PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61. Proc Natl Acad Sci U S A. 2016;113:E4736-44 pubmed publisher
  • western blot; mouse; 1:100; loading ...; fig 2h
Farzana F, Zalm R, Chen N, Li K, Grant S, Smit A, et al. Neurobeachin Regulates Glutamate- and GABA-Receptor Targeting to Synapses via Distinct Pathways. Mol Neurobiol. 2016;53:2112-23 pubmed publisher
  • western blot; mouse; 1:1000
Hoy J, Haeger P, Constable J, Arias R, McCallum R, Kyweriga M, et al. Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions. J Neurosci. 2013;33:9364-84 pubmed publisher
Tao Cheng J, Azzam R, Crocker V, Winters C, Reese T. Depolarization of Hippocampal Neurons Induces Formation of Nonsynaptic NMDA Receptor Islands Resembling Nascent Postsynaptic Densities. Eneuro. 2015;2: pubmed publisher
Levy J, Chen X, Reese T, Nicoll R. Synaptic Consolidation Normalizes AMPAR Quantal Size following MAGUK Loss. Neuron. 2015;87:534-48 pubmed publisher
Farley M, Swulius M, Waxham M. Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities. Neuroscience. 2015;304:286-301 pubmed publisher
Fortin D, Tillo S, Yang G, Rah J, Melander J, Bai S, et al. Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins. J Neurosci. 2014;34:16698-712 pubmed publisher
Williams L, Featherstone D. Regulation of hippocampal synaptic strength by glial xCT. J Neurosci. 2014;34:16093-102 pubmed publisher
de Andrade G, Kunzelman L, Merrill M, Fuerst P. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. Mol Vis. 2014;20:1422-33 pubmed
Lugo J, Smith G, Arbuckle E, White J, Holley A, Floruta C, et al. Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins. Front Mol Neurosci. 2014;7:27 pubmed publisher
Bernard P, Castano A, Bayer K, Benke T. Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures. Neuropharmacology. 2014;84:1-12 pubmed publisher
Bonnet S, Akad D, Samaddar T, Liu Y, Huang X, Dong Y, et al. Synaptic state-dependent functional interplay between postsynaptic density-95 and synapse-associated protein 102. J Neurosci. 2013;33:13398-409 pubmed publisher
Oku Y, Huganir R. AGAP3 and Arf6 regulate trafficking of AMPA receptors and synaptic plasticity. J Neurosci. 2013;33:12586-98 pubmed publisher
Murata Y, Constantine Paton M. Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway. J Neurosci. 2013;33:5040-52 pubmed publisher
Lauks J, Klemmer P, Farzana F, Karupothula R, Zalm R, Cooke N, et al. Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin. PLoS ONE. 2012;7:e39420 pubmed publisher
Wilke S, Hall B, Antonios J, DeNardo L, Otto S, Yuan B, et al. NeuroD2 regulates the development of hippocampal mossy fiber synapses. Neural Dev. 2012;7:9 pubmed publisher
Gardoni F, Zianni E, Eramo A, Canonico P, Di Luca M. Effect of rasagiline on the molecular composition of the excitatory postsynaptic density. Eur J Pharmacol. 2011;670:458-63 pubmed publisher
Mondin M, Labrousse V, Hosy E, Heine M, Tessier B, Levet F, et al. Neurexin-neuroligin adhesions capture surface-diffusing AMPA receptors through PSD-95 scaffolds. J Neurosci. 2011;31:13500-15 pubmed publisher
Etherton M, Földy C, Sharma M, Tabuchi K, Liu X, Shamloo M, et al. Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function. Proc Natl Acad Sci U S A. 2011;108:13764-9 pubmed publisher
Sun Q, Turrigiano G. PSD-95 and PSD-93 play critical but distinct roles in synaptic scaling up and down. J Neurosci. 2011;31:6800-8 pubmed publisher
Chen X, Nelson C, Li X, Winters C, Azzam R, Sousa A, et al. PSD-95 is required to sustain the molecular organization of the postsynaptic density. J Neurosci. 2011;31:6329-38 pubmed publisher
Chen B, Thomas E, Sanz Clemente A, Roche K. NMDA receptor-dependent regulation of dendritic spine morphology by SAP102 splice variants. J Neurosci. 2011;31:89-96 pubmed publisher
Steinmetz C, Turrigiano G. Tumor necrosis factor-? signaling maintains the ability of cortical synapses to express synaptic scaling. J Neurosci. 2010;30:14685-90 pubmed publisher
Delint Ramirez I, Fernández E, Bayés A, Kicsi E, Komiyama N, Grant S. In vivo composition of NMDA receptor signaling complexes differs between membrane subdomains and is modulated by PSD-95 and PSD-93. J Neurosci. 2010;30:8162-70 pubmed publisher
Sumioka A, Yan D, Tomita S. TARP phosphorylation regulates synaptic AMPA receptors through lipid bilayers. Neuron. 2010;66:755-67 pubmed publisher
Petralia R, Wang Y, Hua F, Yi Z, Zhou A, Ge L, et al. Organization of NMDA receptors at extrasynaptic locations. Neuroscience. 2010;167:68-87 pubmed publisher
Fan J, Cowan C, Zhang L, Hayden M, Raymond L. Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease. J Neurosci. 2009;29:10928-38 pubmed publisher
Chaudhury A, He X, Goyal R. Role of PSD95 in membrane association and catalytic activity of nNOSalpha in nitrergic varicosities in mice gut. Am J Physiol Gastrointest Liver Physiol. 2009;297:G806-13 pubmed publisher
Garside M, Turner P, Austen B, Strehler E, Beesley P, Empson R. Molecular interactions of the plasma membrane calcium ATPase 2 at pre- and post-synaptic sites in rat cerebellum. Neuroscience. 2009;162:383-95 pubmed publisher
Al Hallaq R, Conrads T, Veenstra T, Wenthold R. NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus. J Neurosci. 2007;27:8334-43 pubmed
product information
TargetType :
Scaffolds
Target :
SAP102
AccessionNum :
Q62936
Clone :
N19/2
HumanGeneName :
DLG3
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N19_2.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-058
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States