product summary
company name :
Neuromab
product type :
antibody
product name :
Cavbeta4 Ca2+ channel
catalog :
73-054
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
N10/7
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:40
Liu C, Bickford L, Held R, Nyitrai H, Südhof T, Kaeser P. The active zone protein family ELKS supports Ca2+ influx at nerve terminals of inhibitory hippocampal neurons. J Neurosci. 2014;34:12289-303 pubmed publisher
Scamps F, Sangari S, Bowerman M, Rousset M, Bellis M, Cens T, et al. Nerve injury induces a Gem-GTPase-dependent downregulation of P/Q-type Ca2+ channels contributing to neurite plasticity in dorsal root ganglion neurons. Pflugers Arch. 2015;467:351-66 pubmed publisher
Etemad S, Obermair G, Bindreither D, Benedetti A, Stanika R, Di Biase V, et al. Differential neuronal targeting of a new and two known calcium channel ?4 subunit splice variants correlates with their regulation of gene expression. J Neurosci. 2014;34:1446-61 pubmed publisher
Daschil N, Obermair G, Flucher B, Stefanova N, Hutter Paier B, Windisch M, et al. CaV1.2 calcium channel expression in reactive astrocytes is associated with the formation of amyloid-? plaques in an Alzheimer's disease mouse model. J Alzheimers Dis. 2013;37:439-51 pubmed publisher
Ferrándiz Huertas C, Gil Mínguez M, Lujan R. Regional expression and subcellular localization of the voltage-gated calcium channel ? subunits in the developing mouse brain. J Neurochem. 2012;122:1095-107 pubmed publisher
Li L, Cao X, Chen S, Han H, Lopez Berestein G, Sood A, et al. Up-regulation of Cav?3 subunit in primary sensory neurons increases voltage-activated Ca2+ channel activity and nociceptive input in neuropathic pain. J Biol Chem. 2012;287:6002-13 pubmed publisher
Kaeser P, Deng L, Wang Y, Dulubova I, Liu X, Rizo J, et al. RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction. Cell. 2011;144:282-95 pubmed publisher
Ortiz Miranda S, Dayanithi G, Velázquez Marrero C, Custer E, Treistman S, Lemos J. Differential modulation of N-type calcium channels by micro-opioid receptors in oxytocinergic versus vasopressinergic neurohypophysial terminals. J Cell Physiol. 2010;225:276-88 pubmed publisher
Obermair G, Schlick B, Di Biase V, Subramanyam P, Gebhart M, Baumgartner S, et al. Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons. J Biol Chem. 2010;285:5776-91 pubmed publisher
Heneghan J, Mitra Ganguli T, Stanish L, Liu L, Zhao R, Rittenhouse A. The Ca2+ channel beta subunit determines whether stimulation of Gq-coupled receptors enhances or inhibits N current. J Gen Physiol. 2009;134:369-84 pubmed publisher
Abiria S, Colbran R. CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation. J Neurochem. 2010;112:150-61 pubmed publisher
Subramanyam P, Obermair G, Baumgartner S, Gebhart M, Striessnig J, Kaufmann W, et al. Activity and calcium regulate nuclear targeting of the calcium channel beta4b subunit in nerve and muscle cells. Channels (Austin). 2009;3:343-55 pubmed
van Gemert N, Carvalho D, Karst H, van der Laan S, Zhang M, Meijer O, et al. Dissociation between rat hippocampal CA1 and dentate gyrus cells in their response to corticosterone: effects on calcium channel protein and current. Endocrinology. 2009;150:4615-24 pubmed publisher
Klemmer P, Smit A, Li K. Proteomics analysis of immuno-precipitated synaptic protein complexes. J Proteomics. 2009;72:82-90 pubmed publisher
product information
TargetType :
Ca2+ channels
Target :
Cavbeta4 Ca2+ channel
AccessionNum :
XP_215742
Clone :
N10/7
HumanGeneName :
CACNB4
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N10_7.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
ND
Catalog :
73-054
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States