product summary
company name :
Neuromab
product type :
antibody
product name :
Cav1.2/1.3 Ca2+ channel
catalog :
73-053
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
L57/46
reactivity :
rabbit
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 30
Reference
Caballero R, Utrilla R, Amorós I, Matamoros M, Pérez Hernández M, Tinaquero D, et al. Tbx20 controls the expression of the KCNH2 gene and of hERG channels. Proc Natl Acad Sci U S A. 2017;114:E416-E425 pubmed publisher
Assou S, Pourret E, Péquignot M, Rigau V, Kalatzis V, Aït Ahmed O, et al. Cultured Cells from the Human Oocyte Cumulus Niche Are Efficient Feeders to Propagate Pluripotent Stem Cells. Stem Cells Dev. 2015;24:2317-27 pubmed publisher
Kim H, Lee K, Lee D, Han Y, Lee S, Sohn J, et al. Costimulation of AMPA and metabotropic glutamate receptors underlies phospholipase C activation by glutamate in hippocampus. J Neurosci. 2015;35:6401-12 pubmed publisher
Li L, Li D, Chen S, Chen J, Hu H, Pan H. Potentiation of high voltage-activated calcium channels by 4-aminopyridine depends on subunit composition. Mol Pharmacol. 2014;86:760-72 pubmed publisher
Barana A, Matamoros M, Dolz Gait n P, P rez Hern ndez M, Amor s I, N ez M, et al. Chronic atrial fibrillation increases microRNA-21 in human atrial myocytes decreasing L-type calcium current. Circ Arrhythm Electrophysiol. 2014;7:861-8 pubmed publisher
Robert V, Triffaux E, Paulet P, Guéry J, Pelletier L, Savignac M. Protein kinase C-dependent activation of CaV1.2 channels selectively controls human TH2-lymphocyte functions. J Allergy Clin Immunol. 2014;133:1175-83 pubmed publisher
Tajada S, Cidad P, Colinas O, Santana L, López López J, Pérez García M. Down-regulation of CaV1.2 channels during hypertension: how fewer CaV1.2 channels allow more Ca(2+) into hypertensive arterial smooth muscle. J Physiol. 2013;591:6175-91 pubmed publisher
Núñez Santana F, Oh M, Antion M, Lee A, Hell J, Disterhoft J. Surface L-type Ca2+ channel expression levels are increased in aged hippocampus. Aging Cell. 2014;13:111-20 pubmed publisher
Hurley M, Brandon B, Gentleman S, Dexter D. Parkinson's disease is associated with altered expression of CaV1 channels and calcium-binding proteins. Brain. 2013;136:2077-97 pubmed publisher
Bannister J, Leo M, Narayanan D, Jangsangthong W, Nair A, Evanson K, et al. The voltage-dependent L-type Ca2+ (CaV1.2) channel C-terminus fragment is a bi-modal vasodilator. J Physiol. 2013;591:2987-98 pubmed publisher
Bissig D, GOEBEL D, Berkowitz B. Diminished vision in healthy aging is associated with increased retinal L-type voltage gated calcium channel ion influx. PLoS ONE. 2013;8:e56340 pubmed publisher
Valerie N, Dziegielewska B, Hosing A, Augustin E, Gray L, Brautigan D, et al. Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells. Biochem Pharmacol. 2013;85:888-97 pubmed publisher
Cutler M, Wan X, Plummer B, Liu H, Deschenes I, Laurita K, et al. Targeted sarcoplasmic reticulum Ca2+ ATPase 2a gene delivery to restore electrical stability in the failing heart. Circulation. 2012;126:2095-104 pubmed publisher
Wilson S, Schmutzler B, Brittain J, Dustrude E, Ripsch M, Pellman J, et al. Inhibition of transmitter release and attenuation of anti-retroviral-associated and tibial nerve injury-related painful peripheral neuropathy by novel synthetic Ca2+ channel peptides. J Biol Chem. 2012;287:35065-77 pubmed publisher
Ramos Mondragón R, Galindo C, García Castañeda M, Sánchez Vargas J, Vega A, Gómez Viquez N, et al. Chronic potentiation of cardiac L-type Ca(2+) channels by pirfenidone. Cardiovasc Res. 2012;96:244-54 pubmed publisher
Brittain J, Wang Y, Wilson S, Khanna R. Regulation of CREB signaling through L-type Ca2+ channels by Nipsnap-2. Channels (Austin). 2012;6:94-102 pubmed publisher
Larocca T, Fabris F, Chen J, Benhayon D, Zhang S, McCollum L, et al. Na+/Ca2+ exchanger-1 protects against systolic failure in the Akitains2 model of diabetic cardiomyopathy via a CXCR4/NF-?B pathway. Am J Physiol Heart Circ Physiol. 2012;303:H353-67 pubmed publisher
Brandao K, Dell Acqua M, Levinson S. A-kinase anchoring protein 150 expression in a specific subset of TRPV1- and CaV 1.2-positive nociceptive rat dorsal root ganglion neurons. J Comp Neurol. 2012;520:81-99 pubmed publisher
Fu Y, Westenbroek R, Yu F, Clark J, Marshall M, Scheuer T, et al. Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo. J Biol Chem. 2011;286:12617-26 pubmed publisher
Bobe R, Hadri L, Lopez J, Sassi Y, Atassi F, Karakikes I, et al. SERCA2a controls the mode of agonist-induced intracellular Ca2+ signal, transcription factor NFAT and proliferation in human vascular smooth muscle cells. J Mol Cell Cardiol. 2011;50:621-33 pubmed publisher
Altier C, Garcia Caballero A, Simms B, You H, Chen L, Walcher J, et al. The Cav? subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels. Nat Neurosci. 2011;14:173-80 pubmed publisher
Zorrilla de San Martín J, Pyott S, Ballestero J, Katz E. Ca(2+) and Ca(2+)-activated K(+) channels that support and modulate transmitter release at the olivocochlear efferent-inner hair cell synapse. J Neurosci. 2010;30:12157-67 pubmed publisher
Altomare C, Barile L, Marangoni S, Rocchetti M, Alemanni M, Mostacciuolo G, et al. Caffeine-induced Ca(2+) signaling as an index of cardiac progenitor cells differentiation. Basic Res Cardiol. 2010;105:737-49 pubmed publisher
Xu X, Jiang M, Wang Y, Smith T, Baumgarten C, Wood M, et al. Long-term fish oil supplementation induces cardiac electrical remodeling by changing channel protein expression in the rabbit model. PLoS ONE. 2010;5:e10140 pubmed publisher
Wang X, Gao G, Guo K, Yarotskyy V, Huang C, Elmslie K, et al. Phospholemman modulates the gating of cardiac L-type calcium channels. Biophys J. 2010;98:1149-59 pubmed publisher
Fossat P, Dobremez E, Bouali Benazzouz R, Favereaux A, Bertrand S, Kilk K, et al. Knockdown of L calcium channel subtypes: differential effects in neuropathic pain. J Neurosci. 2010;30:1073-85 pubmed publisher
Hettiarachchi N, Parker A, Dallas M, Pennington K, Hung C, Pearson H, et al. alpha-Synuclein modulation of Ca2+ signaling in human neuroblastoma (SH-SY5Y) cells. J Neurochem. 2009;111:1192-201 pubmed publisher
Abiria S, Colbran R. CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation. J Neurochem. 2010;112:150-61 pubmed publisher
Thomsen M, Wang C, Ozgen N, Wang H, Rosen M, Pitt G. Accessory subunit KChIP2 modulates the cardiac L-type calcium current. Circ Res. 2009;104:1382-9 pubmed publisher
Telemaque S, Sonkusare S, Grain T, Rhee S, Stimers J, Rusch N, et al. Design of mutant beta2 subunits as decoy molecules to reduce the expression of functional Ca2+ channels in cardiac cells. J Pharmacol Exp Ther. 2008;325:37-46 pubmed publisher
product information
TargetType :
Ca2+ channels
Target :
Cav1.2/1.3 Ca2+ channel
Clone :
L57/46
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/L57_46.pdf
IsoType :
IgG2b
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
ND
Catalog :
73-053
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States