product summary
company name :
Neuromab
product type :
antibody
product name :
SAP97
catalog :
73-030
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
K64/15
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:50; loading ...; fig 1d
  • western blot; human; 1:50; loading ...; fig 1d
Fragkouli A, Koukouraki P, Vlachos I, Paraskevopoulou M, Hatzigeorgiou A, Doxakis E. Neuronal ELAVL proteins utilize AUF-1 as a co-partner to induce neuron-specific alternative splicing of APP. Sci Rep. 2017;7:44507 pubmed publisher
  • western blot; mouse; 1:1000
Hoy J, Haeger P, Constable J, Arias R, McCallum R, Kyweriga M, et al. Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions. J Neurosci. 2013;33:9364-84 pubmed publisher
Vila A, Whitaker C, O BRIEN J. Membrane-associated guanylate kinase scaffolds organize a horizontal cell synaptic complex restricted to invaginating contacts with photoreceptors. J Comp Neurol. 2017;525:850-867 pubmed publisher
Nagura H, Doi T, Fujiyoshi Y. Characterization of physiological phenotypes of dentate gyrus synapses of PDZ1/2 domain-deficient PSD-95-knockin mice. Eur J Neurosci. 2016;43:618-25 pubmed publisher
Tindi J, Chávez A, Cvejic S, Calvo Ochoa E, Castillo P, Jordan B. ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization. J Neurosci. 2015;35:8986-96 pubmed publisher
Zhang L, Hsu F, Mojsilovic Petrovic J, Jablonski A, Zhai J, Coulter D, et al. Structure-function analysis of SAP97, a modular scaffolding protein that drives dendrite growth. Mol Cell Neurosci. 2015;65:31-44 pubmed publisher
Waters E, Thompson L, Patel P, Gonzales A, Ye H, Filardo E, et al. G-protein-coupled estrogen receptor 1 is anatomically positioned to modulate synaptic plasticity in the mouse hippocampus. J Neurosci. 2015;35:2384-97 pubmed publisher
Fortin D, Tillo S, Yang G, Rah J, Melander J, Bai S, et al. Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins. J Neurosci. 2014;34:16698-712 pubmed publisher
Jafari Z, Esmaili M, Toufan R, Aghamollaei M. Bilingual proficiency and cognitive reserve in Persian-English bilingual older adults. Aging Clin Exp Res. 2015;27:351-7 pubmed publisher
Caffino L, Frankowska M, Giannotti G, Miszkiel J, Sadakierska Chudy A, Racagni G, et al. Cocaine-induced glutamate receptor trafficking is abrogated by extinction training in the rat hippocampus. Pharmacol Rep. 2014;66:198-204 pubmed publisher
Lugo J, Smith G, Arbuckle E, White J, Holley A, Floruta C, et al. Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins. Front Mol Neurosci. 2014;7:27 pubmed publisher
Bustos F, Varela Nallar L, Campos M, Henriquez B, Phillips M, Opazo C, et al. PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors. PLoS ONE. 2014;9:e94037 pubmed publisher
Heller B, Ghidinelli M, Voelkl J, Einheber S, Smith R, Grund E, et al. Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system. J Cell Biol. 2014;204:1219-36 pubmed publisher
Bonnet S, Akad D, Samaddar T, Liu Y, Huang X, Dong Y, et al. Synaptic state-dependent functional interplay between postsynaptic density-95 and synapse-associated protein 102. J Neurosci. 2013;33:13398-409 pubmed publisher
Murata Y, Constantine Paton M. Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway. J Neurosci. 2013;33:5040-52 pubmed publisher
Ng A, Logan A, Schmidt E, Robinson F. The CMT4B disease-causing phosphatases Mtmr2 and Mtmr13 localize to the Schwann cell cytoplasm and endomembrane compartments, where they depend upon each other to achieve wild-type levels of protein expression. Hum Mol Genet. 2013;22:1493-506 pubmed publisher
Nagura H, Ishikawa Y, Kobayashi K, Takao K, Tanaka T, Nishikawa K, et al. Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice. Mol Brain. 2012;5:43 pubmed publisher
Liu W, Chen E, Zhao X, Wan Z, Gao Y, Davey A, et al. The scaffolding protein synapse-associated protein 97 is required for enhanced signaling through isotype-switched IgG memory B cell receptors. Sci Signal. 2012;5:ra54 pubmed publisher
Joseph B, Thakali K, Pathan A, Kang E, Rusch N, Rhee S. Postsynaptic density-95 scaffolding of Shaker-type K? channels in smooth muscle cells regulates the diameter of cerebral arteries. J Physiol. 2011;589:5143-52 pubmed publisher
Sumioka A, Yan D, Tomita S. TARP phosphorylation regulates synaptic AMPA receptors through lipid bilayers. Neuron. 2010;66:755-67 pubmed publisher
Kalashnikova E, Lorca R, Kaur I, Barisone G, Li B, Ishimaru T, et al. SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development. Neuron. 2010;65:80-93 pubmed publisher
Marcello E, Gardoni F, Di Luca M, Pérez Otaño I. An arginine stretch limits ADAM10 exit from the endoplasmic reticulum. J Biol Chem. 2010;285:10376-84 pubmed publisher
Nikandrova Y, Jiao Y, Baucum A, Tavalin S, Colbran R. Ca2+/calmodulin-dependent protein kinase II binds to and phosphorylates a specific SAP97 splice variant to disrupt association with AKAP79/150 and modulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor (AMPAR) activ. J Biol Chem. 2010;285:923-34 pubmed publisher
Al Hallaq R, Conrads T, Veenstra T, Wenthold R. NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus. J Neurosci. 2007;27:8334-43 pubmed
Micheva K, Smith S. Array tomography: a new tool for imaging the molecular architecture and ultrastructure of neural circuits. Neuron. 2007;55:25-36 pubmed
product information
TargetType :
Scaffolds
Target :
SAP97
AccessionNum :
Q62696
Clone :
K64/15
HumanGeneName :
DLG1
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/K64_15.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-030
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States