Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; 1:1000; fig 4
| Bosch M, Nerbonne J, Townsend R, Miyazaki H, Nukina N, Ornitz D, et al. Proteomic analysis of native cerebellar iFGF14 complexes. Channels (Austin). 2016;10:297-312 pubmed publisher
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| Li T, Tian C, Scalmani P, Frassoni C, Mantegazza M, Wang Y, et al. Action potential initiation in neocortical inhibitory interneurons. PLoS Biol. 2014;12:e1001944 pubmed publisher
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- immunohistochemistry - frozen section; mouse; 1:500
| Wang X, Hooks B, Sun Q. Thorough GABAergic innervation of the entire axon initial segment revealed by an optogenetic 'laserspritzer'. J Physiol. 2014;592:4257-76 pubmed publisher
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- immunohistochemistry - paraffin section; rat; 1:500
| Huang C, Chu D, Hwang W, Tsaur M. Coexpression of high-voltage-activated ion channels Kv3.4 and Cav1.2 in pioneer axons during pathfinding in the developing rat forebrain. J Comp Neurol. 2012;520:3650-72 pubmed publisher
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| Yin L, Rasch M, He Q, Wu S, Dou F, Shu Y. Selective Modulation of Axonal Sodium Channel Subtypes by 5-HT1A Receptor in Cortical Pyramidal Neuron. Cereb Cortex. 2017;27:509-521 pubmed publisher
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| Hamada M, Kole M. Myelin loss and axonal ion channel adaptations associated with gray matter neuronal hyperexcitability. J Neurosci. 2015;35:7272-86 pubmed publisher
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| Wildburger N, Ali S, Hsu W, Shavkunov A, Nenov M, Lichti C, et al. Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain. Mol Cell Proteomics. 2015;14:1288-300 pubmed publisher
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| Wimmer V, Harty R, Richards K, Phillips A, Miyazaki H, Nukina N, et al. Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain. J Comp Neurol. 2015;523:814-30 pubmed publisher
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| Gazina E, Leaw B, Richards K, Wimmer V, Kim T, Aumann T, et al. 'Neonatal' Nav1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour. Hum Mol Genet. 2015;24:1457-68 pubmed publisher
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| Tian C, Wang K, Ke W, Guo H, Shu Y. Molecular identity of axonal sodium channels in human cortical pyramidal cells. Front Cell Neurosci. 2014;8:297 pubmed publisher
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| Baek J, Rubinstein M, Scheuer T, Trimmer J. Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures. J Biol Chem. 2014;289:15363-73 pubmed publisher
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| Liu W, Deng J, Wang G, Zhang C, Luo X, Yan D, et al. KCNE2 modulates cardiac L-type Ca(2+) channel. J Mol Cell Cardiol. 2014;72:208-18 pubmed publisher
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| Vega A, Avila G, Matthews G. Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression. Sci Rep. 2013;3:2809 pubmed publisher
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| He Y, Liu D, Fang Y, Zhan X, Yao J, Mei Y. Exposure to extremely low-frequency electromagnetic fields modulates Na+ currents in rat cerebellar granule cells through increase of AA/PGE2 and EP receptor-mediated cAMP/PKA pathway. PLoS ONE. 2013;8:e54376 pubmed publisher
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| Martínez Hernández J, Ballesteros Merino C, Fernandez Alacid L, Nicolau J, Aguado C, Lujan R. Polarised localisation of the voltage-gated sodium channel Na(v)1.2 in cerebellar granule cells. Cerebellum. 2013;12:16-26 pubmed publisher
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| Dhaunchak A, Becker C, Schulman H, de Faria O, Rajasekharan S, Banwell B, et al. Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis. Ann Neurol. 2012;71:601-13 pubmed publisher
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| Kaphzan H, Buffington S, Jung J, Rasband M, Klann E. Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome. J Neurosci. 2011;31:17637-48 pubmed publisher
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| Lysakowski A, Gaboyard Niay S, Calin Jageman I, Chatlani S, Price S, Eatock R. Molecular microdomains in a sensory terminal, the vestibular calyx ending. J Neurosci. 2011;31:10101-14 pubmed publisher
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| Wykes R, Kalmbach A, Eliava M, Waters J. Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice. Neurobiol Aging. 2012;33:1609-23 pubmed publisher
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| Ahn H, Black J, Zhao P, Tyrrell L, Waxman S, Dib Hajj S. Nav1.7 is the predominant sodium channel in rodent olfactory sensory neurons. Mol Pain. 2011;7:32 pubmed publisher
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| Barry J, Gu Y, Gu C. Polarized targeting of L1-CAM regulates axonal and dendritic bundling in vitro. Eur J Neurosci. 2010;32:1618-31 pubmed publisher
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| Wimmer V, Reid C, Mitchell S, Richards K, Scaf B, Leaw B, et al. Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus. J Clin Invest. 2010;120:2661-71 pubmed publisher
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| Lorincz A, Nusser Z. Molecular identity of dendritic voltage-gated sodium channels. Science. 2010;328:906-9 pubmed publisher
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| Wimmer V, Reid C, So E, Berkovic S, Petrou S. Axon initial segment dysfunction in epilepsy. J Physiol. 2010;588:1829-40 pubmed publisher
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| Liao Y, Deprez L, Maljevic S, Pitsch J, Claes L, Hristova D, et al. Molecular correlates of age-dependent seizures in an inherited neonatal-infantile epilepsy. Brain. 2010;133:1403-14 pubmed publisher
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| Black J, Newcombe J, Waxman S. Astrocytes within multiple sclerosis lesions upregulate sodium channel Nav1.5. Brain. 2010;133:835-46 pubmed publisher
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| Brackenbury W, Calhoun J, Chen C, Miyazaki H, Nukina N, Oyama F, et al. Functional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth. Proc Natl Acad Sci U S A. 2010;107:2283-8 pubmed publisher
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| Berendt F, Park K, Trimmer J. Multisite phosphorylation of voltage-gated sodium channel alpha subunits from rat brain. J Proteome Res. 2010;9:1976-84 pubmed publisher
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| Bouvier D, Tremblay M, Riad M, Corera A, Gingras D, Horn K, et al. EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain. J Neurochem. 2010;113:153-65 pubmed publisher
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| Conant K, Wang Y, Szklarczyk A, Dudak A, Mattson M, Lim S. Matrix metalloproteinase-dependent shedding of intercellular adhesion molecule-5 occurs with long-term potentiation. Neuroscience. 2010;166:508-21 pubmed publisher
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| Merrick E, Kalmar C, Snyder S, Cusdin F, Yu E, Sando J, et al. The importance of serine 161 in the sodium channel beta3 subunit for modulation of Na(V)1.2 gating. Pflugers Arch. 2010;460:743-53 pubmed publisher
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| Crawford D, Mangiardi M, Xia X, López Valdés H, Tiwari Woodruff S. Functional recovery of callosal axons following demyelination: a critical window. Neuroscience. 2009;164:1407-21 pubmed publisher
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| Thomas E, Hawkins R, Richards K, Xu R, Gazina E, Petrou S. Heat opens axon initial segment sodium channels: a febrile seizure mechanism?. Ann Neurol. 2009;66:219-26 pubmed publisher
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| von Reyn C, Spaethling J, Mesfin M, Ma M, Neumar R, Smith D, et al. Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit. J Neurosci. 2009;29:10350-6 pubmed publisher
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| Kress G, Dowling M, Eisenman L, Mennerick S. Axonal sodium channel distribution shapes the depolarized action potential threshold of dentate granule neurons. Hippocampus. 2010;20:558-71 pubmed publisher
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| O Malley H, Shreiner A, Chen G, Huffnagle G, Isom L. Loss of Na+ channel beta2 subunits is neuroprotective in a mouse model of multiple sclerosis. Mol Cell Neurosci. 2009;40:143-55 pubmed publisher
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| Lonigro A, Devaux J. Disruption of neurofascin and gliomedin at nodes of Ranvier precedes demyelination in experimental allergic neuritis. Brain. 2009;132:260-73 pubmed publisher
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| Mojumder D, Wensel T, Frishman L. Subcellular compartmentalization of two calcium binding proteins, calretinin and calbindin-28 kDa, in ganglion and amacrine cells of the rat retina. Mol Vis. 2008;14:1600-13 pubmed
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| Vega A, Henry D, Matthews G. Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a. Neurosci Lett. 2008;442:69-73 pubmed publisher
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| Zhao P, Barr T, Hou Q, Dib Hajj S, Black J, Albrecht P, et al. Voltage-gated sodium channel expression in rat and human epidermal keratinocytes: evidence for a role in pain. Pain. 2008;139:90-105 pubmed publisher
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| Mojumder D, Frishman L, Otteson D, Sherry D. Voltage-gated sodium channel alpha-subunits Na(v)1.1, Na(v)1.2, and Na(v)1.6 in the distal mammalian retina. Mol Vis. 2007;13:2163-82 pubmed
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