product summary
company name :
Neuromab
product type :
antibody
product name :
Kvbeta2/KCNAB2 K+ channel
catalog :
73-021
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
K17/70
reactivity :
zebra finch, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, western blot knockout validation
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; zebra finch; 1:250
Condro M, White S. Distribution of language-related Cntnap2 protein in neural circuits critical for vocal learning. J Comp Neurol. 2014;522:169-85 pubmed publisher
Nguyen L, Anderson A. mTOR-dependent alterations of Kv1.1 subunit expression in the neuronal subset-specific Pten knockout mouse model of cortical dysplasia with epilepsy. Sci Rep. 2018;8:3568 pubmed publisher
Huang C, Zhang C, Zollinger D, Leterrier C, Rasband M. An αII Spectrin-Based Cytoskeleton Protects Large-Diameter Myelinated Axons from Degeneration. J Neurosci. 2017;37:11323-11334 pubmed publisher
Kole M, Qian J, Waase M, Klassen T, Chen T, Augustine G, et al. Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. J Neurosci. 2015;35:11433-44 pubmed publisher
Bavassano C, Marvaldi L, Langeslag M, Sarg B, Lindner H, Klimaschewski L, et al. Identification of voltage-gated K(+) channel beta 2 (Kv?2) subunit as a novel interaction partner of the pain transducer Transient Receptor Potential Vanilloid 1 channel (TRPV1). Biochim Biophys Acta. 2013;1833:3166-3175 pubmed publisher
Ovsepian S, Steuber V, Le Berre M, O Hara L, O Leary V, Dolly J. A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets. J Physiol. 2013;591:1771-91 pubmed publisher
Williams M, Fuchs J, Green J, Morielli A. Cellular mechanisms and behavioral consequences of Kv1.2 regulation in the rat cerebellum. J Neurosci. 2012;32:9228-37 pubmed publisher
Tipparaju S, Li X, Kilfoil P, Xue B, Uversky V, Bhatnagar A, et al. Interactions between the C-terminus of Kv1.5 and Kv? regulate pyridine nucleotide-dependent changes in channel gating. Pflugers Arch. 2012;463:799-818 pubmed publisher
Duflocq A, Chareyre F, Giovannini M, Couraud F, Davenne M. Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B. BMC Biol. 2011;9:66 pubmed publisher
Gu C, Gu Y. Clustering and activity tuning of Kv1 channels in myelinated hippocampal axons. J Biol Chem. 2011;286:25835-47 pubmed publisher
Cheng L, Yung A, Covarrubias M, Radice G. Cortactin is required for N-cadherin regulation of Kv1.5 channel function. J Biol Chem. 2011;286:20478-89 pubmed publisher
Ohnishi H, Murata T, Kusakari S, Hayashi Y, Takao K, Maruyama T, et al. Stress-evoked tyrosine phosphorylation of signal regulatory protein ? regulates behavioral immobility in the forced swim test. J Neurosci. 2010;30:10472-83 pubmed publisher
Stapels M, Piper C, Yang T, Li M, Stowell C, Xiong Z, et al. Polycomb group proteins as epigenetic mediators of neuroprotection in ischemic tolerance. Sci Signal. 2010;3:ra15 pubmed publisher
Pineda R, Knoeckel C, Taylor A, Estrada Bernal A, Ribera A. Kv1 potassium channel complexes in vivo require Kvbeta2 subunits in dorsal spinal neurons. J Neurophysiol. 2008;100:2125-36 pubmed publisher
Ogawa Y, Horresh I, Trimmer J, Bredt D, Peles E, Rasband M. Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2. J Neurosci. 2008;28:5731-9 pubmed publisher
Wenzel H, Vacher H, Clark E, Trimmer J, Lee A, Sapolsky R, et al. Structural consequences of Kcna1 gene deletion and transfer in the mouse hippocampus. Epilepsia. 2007;48:2023-46 pubmed
Gu C, Zhou W, Puthenveedu M, Xu M, Jan Y, Jan L. The microtubule plus-end tracking protein EB1 is required for Kv1 voltage-gated K+ channel axonal targeting. Neuron. 2006;52:803-16 pubmed
product information
TargetType :
K+ channels
Target :
Kvbeta2/KCNAB2 K+ channel
AccessionNum :
P62482
Clone :
K17/70
HumanGeneName :
KCNAB2
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/K17_70.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
Catalog :
73-021
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States