product summary
company name :
Neuromab
product type :
antibody
product name :
Kv1.4 K+ channel
catalog :
73-010
quantity :
5 ml
price :
269 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
K13/31
reactivity :
rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 35
Reference
Zhou L, Zhou L, Su L, Cao S, Xie Y, Wang N, et al. Celecoxib Ameliorates Seizure Susceptibility in Autosomal Dominant Lateral Temporal Epilepsy. J Neurosci. 2018;38:3346-3357 pubmed publisher
Nguyen L, Anderson A. mTOR-dependent alterations of Kv1.1 subunit expression in the neuronal subset-specific Pten knockout mouse model of cortical dysplasia with epilepsy. Sci Rep. 2018;8:3568 pubmed publisher
Zhang X, Ai X, Nakayama H, Chen B, Harris D, Tang M, et al. Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias. Basic Res Cardiol. 2016;111:4 pubmed publisher
Cobb M, Austin D, Sack J, Trimmer J. Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells. J Biol Chem. 2015;290:29189-201 pubmed publisher
Kole M, Qian J, Waase M, Klassen T, Chen T, Augustine G, et al. Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. J Neurosci. 2015;35:11433-44 pubmed publisher
Lee K, Royston S, Vest M, Ley D, Lee S, Bolton E, et al. N-methyl-D-aspartate receptors mediate activity-dependent down-regulation of potassium channel genes during the expression of homeostatic intrinsic plasticity. Mol Brain. 2015;8:4 pubmed publisher
Mulholland P, Spencer K, Hu W, Kroener S, Chandler L. Neuroplasticity of A-type potassium channel complexes induced by chronic alcohol exposure enhances dendritic calcium transients in hippocampus. Psychopharmacology (Berl). 2015;232:1995-2006 pubmed publisher
Dufour M, Woodhouse A, Goaillard J. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development. J Neurosci Res. 2014;92:981-99 pubmed publisher
Speca D, Ogata G, Mandikian D, Bishop H, Wiler S, Eum K, et al. Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability. Genes Brain Behav. 2014;13:394-408 pubmed publisher
Fan L, Guan X, Wang W, Zhao J, Zhang H, Tiwari V, et al. Impaired neuropathic pain and preserved acute pain in rats overexpressing voltage-gated potassium channel subunit Kv1.2 in primary afferent neurons. Mol Pain. 2014;10:8 pubmed publisher
Wang W, Kim H, Lv P, TEMPEL B, Yamoah E. Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses. J Neurophysiol. 2013;110:1751-64 pubmed publisher
Zhao X, Tang Z, Zhang H, Atianjoh F, Zhao J, Liang L, et al. A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons. Nat Neurosci. 2013;16:1024-31 pubmed publisher
Brewster A, Lugo J, Patil V, Lee W, Qian Y, Vanegas F, et al. Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage. PLoS ONE. 2013;8:e57808 pubmed publisher
Ovsepian S, Steuber V, Le Berre M, O Hara L, O Leary V, Dolly J. A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets. J Physiol. 2013;591:1771-91 pubmed publisher
Zhu Y, Colak T, Shenoy M, Liu L, Mehta K, Pai R, et al. Transforming growth factor beta induces sensory neuronal hyperexcitability, and contributes to pancreatic pain and hyperalgesia in rats with chronic pancreatitis. Mol Pain. 2012;8:65 pubmed publisher
DiFranco M, QuiƱonez M, Vergara J. The delayed rectifier potassium conductance in the sarcolemma and the transverse tubular system membranes of mammalian skeletal muscle fibers. J Gen Physiol. 2012;140:109-37 pubmed publisher
Menegola M, Clark E, Trimmer J. The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice. Epilepsia. 2012;53 Suppl 1:142-9 pubmed publisher
Jukkola P, Lovett Racke A, Zamvil S, Gu C. K+ channel alterations in the progression of experimental autoimmune encephalomyelitis. Neurobiol Dis. 2012;47:280-93 pubmed publisher
Sun W, MAFFIE J, Lin L, Petralia R, Rudy B, Hoffman D. DPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neurons. Neuron. 2011;71:1102-15 pubmed publisher
Cheng L, Yung A, Covarrubias M, Radice G. Cortactin is required for N-cadherin regulation of Kv1.5 channel function. J Biol Chem. 2011;286:20478-89 pubmed publisher
Guan D, Horton L, Armstrong W, FOEHRING R. Postnatal development of A-type and Kv1- and Kv2-mediated potassium channel currents in neocortical pyramidal neurons. J Neurophysiol. 2011;105:2976-88 pubmed publisher
Al Sabi A, Kaza S, Le Berre M, O Hara L, Bodeker M, Wang J, et al. Position-dependent attenuation by Kv1.6 of N-type inactivation of Kv1.4-containing channels. Biochem J. 2011;438:389-96 pubmed publisher
Fulton S, Thibault D, Mendez J, Lahaie N, Tirotta E, Borrelli E, et al. Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow. J Biol Chem. 2011;286:9360-72 pubmed publisher
Ohnishi H, Murata T, Kusakari S, Hayashi Y, Takao K, Maruyama T, et al. Stress-evoked tyrosine phosphorylation of signal regulatory protein ? regulates behavioral immobility in the forced swim test. J Neurosci. 2010;30:10472-83 pubmed publisher
Xu X, Jiang M, Wang Y, Smith T, Baumgarten C, Wood M, et al. Long-term fish oil supplementation induces cardiac electrical remodeling by changing channel protein expression in the rabbit model. PLoS ONE. 2010;5:e10140 pubmed publisher
Ogawa Y, Oses Prieto J, Kim M, Horresh I, Peles E, Burlingame A, et al. ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons. J Neurosci. 2010;30:1038-48 pubmed publisher
Usman H, Mathew M. Potassium channel regulator KCNRG regulates surface expression of Shaker-type potassium channels. Biochem Biophys Res Commun. 2010;391:1301-5 pubmed publisher
Cartwright T, Schwalbe R. Atypical sialylated N-glycan structures are attached to neuronal voltage-gated potassium channels. Biosci Rep. 2009;29:301-13 pubmed publisher
Monaghan M, Menegola M, Vacher H, Rhodes K, Trimmer J. Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy. Neuroscience. 2008;156:550-62 pubmed publisher
Buniel M, Glazebrook P, Ramirez Navarro A, Kunze D. Distribution of voltage-gated potassium and hyperpolarization-activated channels in sensory afferent fibers in the rat carotid body. J Comp Neurol. 2008;510:367-77 pubmed publisher
Kim J, Nadal M, Clemens A, Baron M, Jung S, Misumi Y, et al. Kv4 accessory protein DPPX (DPP6) is a critical regulator of membrane excitability in hippocampal CA1 pyramidal neurons. J Neurophysiol. 2008;100:1835-47 pubmed publisher
Ogawa Y, Horresh I, Trimmer J, Bredt D, Peles E, Rasband M. Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2. J Neurosci. 2008;28:5731-9 pubmed publisher
Wenzel H, Vacher H, Clark E, Trimmer J, Lee A, Sapolsky R, et al. Structural consequences of Kcna1 gene deletion and transfer in the mouse hippocampus. Epilepsia. 2007;48:2023-46 pubmed
Vacher H, Mohapatra D, Misonou H, Trimmer J. Regulation of Kv1 channel trafficking by the mamba snake neurotoxin dendrotoxin K. FASEB J. 2007;21:906-14 pubmed
Pott C, Ren X, Tran D, Yang M, Henderson S, Jordan M, et al. Mechanism of shortened action potential duration in Na+-Ca2+ exchanger knockout mice. Am J Physiol Cell Physiol. 2007;292:C968-73 pubmed
product information
TargetType :
K+ channels
Target :
Kv1.4 K+ channel
AccessionNum :
P15385
Clone :
K13/31
HumanGeneName :
KCNA4
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/K13_31.pdf
IsoType :
IgG1
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
ND
Catalog :
73-010
more info or order :
company information
Neuromab
PO Box 1560 Davis, CA 95617-1560
http://neuromab.ucdavis.edu
headquarters: United States