product summary
company name :
Nanotools
product type :
antibody
product name :
LC3-I (18 kDa); LC3-II (16 kDa)
catalog :
0260-100/LC3-2G6
quantity :
100 µg
price :
332,00 EURO
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G6
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig ev2b
Zaffagnini G, Savova A, Danieli A, Romanov J, Tremel S, Ebner M, et al. p62 filaments capture and present ubiquitinated cargos for autophagy. EMBO J. 2018;37: pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 6m
  • western blot; mouse; 1:100; loading ...; fig 2e
Gstrein T, Edwards A, Přistoupilová A, Leca I, Breuss M, Pilat Carotta S, et al. Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans. Nat Neurosci. 2018;21:207-217 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 4b
de Oliveira R, Vicente Miranda H, Francelle L, Pinho R, Szego E, Martinho R, et al. The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. PLoS Biol. 2017;15:e2000374 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 3e
Vicente Miranda H, Gomes M, Branco Santos J, Breda C, Lázaro D, Lopes L, et al. Glycation potentiates neurodegeneration in models of Huntington's disease. Sci Rep. 2016;6:36798 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 5
Jennewein L, Ronellenfitsch M, Antonietti P, Ilina E, Jung J, Stadel D, et al. Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas. Oncotarget. 2016;7:20016-32 pubmed publisher
  • western blot; human; fig 8
Brohée L, Demine S, Willems J, Arnould T, Colige A, Deroanne C. Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment. Oncotarget. 2015;6:11264-80 pubmed
  • immunocytochemistry; human
  • western blot; human
Zhong Y, Morris D, Jin L, Patel M, Karunakaran S, Fu Y, et al. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels. J Biol Chem. 2014;289:26021-37 pubmed publisher
Nakajima H, Itakura M, Kubo T, Kaneshige A, Harada N, Izawa T, et al. Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death. J Biol Chem. 2017;292:4727-4742 pubmed publisher
Stamelos V, Fisher N, Bamrah H, Voisey C, Price J, Farrell W, et al. The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization. PLoS ONE. 2016;11:e0150696 pubmed publisher
Khaminets A, Heinrich T, Mari M, Grumati P, Huebner A, Akutsu M, et al. Regulation of endoplasmic reticulum turnover by selective autophagy. Nature. 2015;522:354-8 pubmed publisher
company information
Nanotools
Tscheulinstr. 21 D-79331 Teningen
http://www.nanotools.de
headquarters: Germany