Recombinant human UbcH8/UBE2L6 protein | NKMAX UBE0901 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human UbcH8/UBE2L6 protein

catalog :

UBE0901

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human UbcH8/UBE2L6 protein

Domain :

1-152aa

Catalog number (SKU) :

UBE0901

NCBI :

NP_004214

Description :

ubiquitin-conjugating enzyme E2L6 (uBE2L6), also known as ubcH8, is a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. ubiquitination of a protein substrate requires the concerted action of 3 classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin protein ligases. The E2 ubiquitin-conjugating enzyme is highly similar in primary structure to the enzyme encoded by uBE2L3 gene. Recombinant human uBE2L6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Ubiquitin conjugating enzyme E2 L6, Ubiquitin/ISG15-conjugating enzyme E2 L6, E2 ubiquitin-conjugating enzyme L6, Retinoic acid-induced gene B protein, RIG-B, UbcH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1mM PMSF, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ardley HC., et al. (2000) Cytogenet Cell Genet. 89(1-2):137-140.;; Movnihan TP., et al. (1999) J Biol Chem. 274(43):30963-30968. ;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Ubiquitination

Molecular Weight :

21.7 kDa (188aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMASM RVVKELEDLQ KKPPPYLRNL SSDDANVLVW HALLLPDQPP YHLKAFNLRI SFPPEYPFKP PMIKFTTKIY HPNVDENGQI CLPIISSENW KPCTKTCQVL EALNVLVNRP NIREPLRMDL ADLLTQNPEL FRKNAEEFTL RFGVDRPS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O14933

Internal Search Terms :

UbcH8, UBE2L6,UBE0901-10ug,UBE0901-20ug,UBE0901-50ug,UBE0901-100ug,UBE0901-250ug,UBE0901-500ug,UBE0901-1mg,UBE0901-10,UBE0901-20,UBE0901-50,UBE0901-100,UBE0901-250,UBE0901-500,UBE0901-1

more info or order :

NKMAX product webpage