protein

Recombinant human alpha-Synuclein (Delta-NAC) protein

SNA2008

20 ug

55 USD

Recombinant human alpha-Synuclein (Delta-NAC) protein

SNA2008

NP_000336.1

A deletion mutant of alpha-synuclein that lacks the NAC region (amino acid 61-95). alpha-synuclein (deltaNAC) was overexpressed in E. coli and purified to apparent homogeneity by taking advantage of the thermosolubility of the protein and by using conventional column chromatography techniques. 6 amino acids were added as a linker.

SNCA, NACP, PARK1, PARK4, PD1, α-synuclein Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Parkinson disease 4, autosomal dominant Lewy body

1mg/ml (determined by BCA assay)

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

ueda., et al. (1993) Proc. Natl.Acad.Sci. 90, 11282-11286.

> 95% by SDS-PAGE

SDS-PAGE

Human

Neuroscience

11.9 kDa (111aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK GTEIWMKKDQ LGKNEEGAPQ EGILEDMPVD PDNEAYEMPS EEGYQDYEPE A

Non-Tagged

E.coli

Recombinant Protein

P37840

a-Synuclein (Delta-NAC), SNCA, NACP, PARK1, alpha-Synuclein Delta-NAC, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, Alpha-synuclein, Alpha synuclein, Alpha-synuclein, isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid, precursor of, PARK 1, PARK 4, PARK4, Parkinson disease familial 1, PD 1, PD1, Snca synuclein, alpha (non A4 component of amyloid precursor), Synuclein alpha, Synuclein, alpha (non A4 component of amyloid precursor),SNA2008-10ug,SNA2008-20ug,SNA2008-50ug,SNA2008-100ug,SNA2008-250ug,SNA2008-500ug,SNA2008-1mg,SNA2008-10,SNA2008-20,SNA2008-50,SNA2008-100,SNA2008-250,SNA2008-500,SNA2008-1

;;Kawakami F, et al. Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β. (FEBS J. 2011){https://pubmed.ncbi.nlm.nih.gov/21985244/}