Recombinant human Sirtulin 6/SIRT6 protein | NKMAX SIR0901 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Sirtulin 6/SIRT6 protein

catalog :

SIR0901

quantity :

20 ug

price :

160 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Sirtulin 6/SIRT6 protein

Domain :

1-355aa

Catalog number (SKU) :

SIR0901

NCBI :

NP_057623

Description :

The SIRT6 is included in class IV of the sirtuin family, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined; however, in yeast sirtuins are known to regulate epigenetic gene silencing. Also SIRT6, a chromatin-associated protein, appears to be involved in DNA repair. Recombinant SIRT6, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography techniques.

Alternative Names :

NAD-dependent protein deacylase sirtuin-6, Protein mono-ADP-ribosyltransferase sirtuin-6, Regulatory protein SIR2 homolog 6, SIR2-like protein 6, SIR2L6

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 20% glycerol, 1mM DTT, 0.1M NaCl, 0.1mM PMSF

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Michishita E., et al. (2008) Nature. 452(7186):492-6.;; Mostoslavsky R., et al. (2006) Cell. 124(2):315-29.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

41 kDa (375aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MSVNYAAGLS PYADKGKCGL PEIFDPPEEL ERKVWELARL VWQSSSVVFH TGAGISTASG IPDFRGPHGV WTMEERGLAP KFDTTFESAR PTQTHMALVQ LERVGLLRFL VSQNVDGLHV RSGFPRDKLA ELHGNMFVEE CAKCKTQYVR DTVVGTMGLK ATGRLCTVAK ARGLRACRGE LRDTILDWED SLPDRDLALA DEASRNADLS ITLGTSLQIR PSGNLPLATK RRGGRLVIVN LQPTKHDRHA DLRIHGYVDE VMTRLMKHLG LEIPAWDGPR VLERALPPLP RPPTPKLEPK EESPTRINGS IPAGPKQEPC AQHNGSEPAS PKRERPTSPA PHRPPKRVKA KAVPS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q8N6T7

Internal Search Terms :

Mono-ADP-ribosyltransferase sirtuin-6, NAD-dependent protein deacylase sirtuin-6, Protein mono-ADP-ribosyltransferase sirtuin-6, Regulatory protein SIR2 homolog 6, SIR2 like protein 6, SIR2 related protein type 6, SIR2L6, SIR2-like protein 6, SIRT 6, SIRT6, Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), Sirtuin 6, Sirtuin 6 Mono ADP ribosyltransferase sirtuin 6, Sirtuin type 6, Sirtuin6, SIR0901-10ug, SIR0901-20ug, SIR0901-50ug, SIR0901-100ug, SIR0901-250ug, SIR0901-500ug, SIR0901-1mg, SIR0901-010, SIR0901-020, SIR0901-050, SIR0901-100, SIR0901-250, SIR0901-500, SIR0901-01M

more info or order :

NKMAX product webpage