Recombinant human RXR alpha/RXRA protein | NKMAX RXR3001 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RXR alpha/RXRA protein

catalog :

RXR3001

quantity :

20 ug

price :

55 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RXR alpha/RXRA protein

Domain :

111-228aa

Catalog number (SKU) :

RXR3001

NCBI :

NP_002948.1

Description :

The retinoid X receptor (RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors (RAR), thyroid hormone receptors (TR), vitamin D receptors and peroxisome proliferators-activated receptors (PPAR). The RXR family includes three difference isoforms ; RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34. 9 and encodes two major isoforms (RXR alpha1, RXR alpha2). The DNA binding domain of RXR (111-228aa) was over expressed in E. coli and purified by using conventional column chromatography techniques.

Alternative Names :

RXRA, NR2B1, RXR-alpha, Retinoid X receptor, Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1, Retinoic acid receptor RXR-alpha, FLJ16020, FLJ16733, MGC102720, Retinoic acid receptor RXR alpha, RXR alpha1, RXRA1

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl, 5mM beta-Mercaptoethanol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Si J., et al. (2002) Blood, 100(13);;4401-9.;; Zeng M., et al. (2002) J. Biol. Chem. 277(47):45611-8.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

13.5 kDa (119aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P19793

Internal Search Terms :

RXRalpha1, RXR-alpha, RXRalpha, RXRA1, RXR-a, RXRA, RXR alpha1, RXR alpha 1, RXR alpha, RXR A, Retinoid X receptor alpha, Retinoid X receptor, Retinoic acid receptor RXR-alpha, Retinoic acid receptor RXR alpha, Nuclear receptor subfamily 2 group B member 1, NR2B1, MGC102720, FLJ16733, FLJ16020, RXR3001-10ug, RXR3001-20ug, RXR3001-50ug, RXR3001-100ug, RXR3001-250ug, RXR3001-500ug, RXR3001-1mg, RXR3001-010, RXR3001-020, RXR3001-050, RXR3001-100, RXR3001-250, RXR3001-500, RXR3001-01M

more info or order :

NKMAX product webpage