product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human RAR alpha/NR1B1 protein
catalog :
RAR0801
quantity :
20 ug
price :
80 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human RAR alpha/NR1B1 protein
Domain :
68-173aa
Catalog number (SKU) :
RAR0801
NCBI :
NP_000955
Description :
Retinoic acid receptors (RAR) belong to the large family of ligand responsive gene regulatory proteins that includes receptors for steroid and thyroid hormones. These proteins contain two highly conserved domains that are involved in determining their DNA and ligand-binding activities. Three isotypes of RARs, alpha, beta, and gamma, are encoded by distinct genetic loci and possess distinct transcriptional properties. Typically, RAR-alpha represses target gene transcription in the absence of hormone, whereas RAR-beta and gamma fail to repress under these conditions. Recombinant human RARalpha, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Retinoic acid receptor alpha isoform 1, NR1B1, Retinoic acid receptor alpha, Retinoic acid receptor, alpha isoform 1, RAR alpha, RARalpha, RAR, Retinoic acid receptor, alpha isoform 1
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol, 1mM DTT, 0.1M NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Kliewer SA., et al. (1992) Nature. 355, 446-9.;; Gillespie RF., et al. (2007) J. Biol. Chem. 282, 33421-34.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cell Cycle
Molecular Weight :
14 kDa (127aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Amino Acid Sequence :
MSEEIVPSPP SPPPLPRIYK PCFVCQDKSS GYHYGVSACE GCKGFFRRSI QKNMVYTCHR DKNCIINKVT RNRCQYCRLQ KCFEVGMSKE SVRNDRNKKK KEVPKPE
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P10276
Internal Search Terms :
RAR a, NR1B1, Retinoic acid receptor alpha isoform 1, NR1B1, Retinoic acid receptor alpha, Retinoic acid receptor, alpha isoform 1, RAR alpha, RARalpha, RAR, Retinoic acid receptor, alpha isoform 1,RAR0801-10ug,RAR0801-20ug,RAR0801-50ug,RAR0801-100ug,RAR0801-250ug,RAR0801-500ug,RAR0801-1mg,RAR0801-10,RAR0801-20,RAR0801-50,RAR0801-100,RAR0801-250,RAR0801-500,RAR0801-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.