protein

Recombinant human PTH protein

PTH3001

20 ug

55 USD

Recombinant human PTH protein

32-115aa

PTH3001

NP_000306.1

Human parathyroid hormone (hPTH) is an 84 amino acid residue peptide and one of the main regulators in maintenance of calcium homeostasis. It acts primarily on kidney and bone cells stimulating calcium back resorption or calcium mobilization, respectively. The whole mechanism is still under discussion, but low-dose hPTH triggers cyclic AMP-dependent protein kinase in some populations of bone cells bearing PTH receptors, which stimulates the proliferation of osteoblasts. Human parathyroid hormone (amino acids 1-84) was overexpressed in E. coli and purified to apparent homogeneity by using conventional column chromatography techniques

PTH, Human Parathyroid Hormone, PTH, Parathyrin, Parathormone, Parathyroid hormone, hPTH, Parathormone,

1mg/ml (determined by absorbance at 280nm)

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 2mM EDTA

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Hodsman AB. et al. (2003) J. Clin. Endocrinol. Metab. 88(11), 5212-20.;; Wingender E., et al. (1989) J. Biol. Chem. 264(8),4367-73.;;

> 90% by SDS-PAGE

SDS-PAGE

Human

Hormones & Cytokines

9.55 kDa (85aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

MSVSEIQLMH NLGKHLNSME RVEWLRKKLQ DVHNFVALGA PLAPRDAGSQ RPRKKEDNVL VESHEKSLGE ADKADVNVLT KAKSQ

Non-Tagged

E.coli

Recombinant Protein

P01270

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Zhang H, et al. Facile detection of proteins on a solid-phase membrane by direct binding of dextran-based luminol-biotin chemiluminescent polymer. (Talanta. 2009){https://pubmed.ncbi.nlm.nih.gov/19576433/}