Recombinant human Phosphoserine phosphatase/PSPH protein

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Phosphoserine phosphatase/PSPH protein

catalog :

PSP0501

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Phosphoserine phosphatase/PSPH protein

Domain :

1-225aa

Catalog number (SKU) :

PSP0501

NCBI :

NP_004568.2

Description :

Human Phosphoserine phosphatase (hPSP) is an important enzyme in the phosphorylated pathway of serine biosynthesis, which contributes a major portion of the endogenous L-serine. Similar to known L-3-phosphoserine phosphatases, it catalyzed the Mg2+ General references: -dependent hydrolysis of L-phosphoserine and an exchange reaction between L-serine and L-phosphoserine. Recently, its complex structures reveal that the open-closed environmental change of the active site, generated by local rearrangement of the alpha-helical bundle domain, is important to substrate recognition and hydrolysis. Recombinant human hPSP was overexpressed in E. coli and purified by conventional chromatography.

Alternative Names :

PSPH, Phosphoserine phosphatase Human, PSPase, PSP, EC 3.1.3.3, O-phosphoserine phosphohydrolase, L-3-phosphoserine phosphatase, Phosphoserine phosphatase, L 3 phosphoserine phosphatase, O phosphoserine phosphohydrolase, Phosphoserine phosphatase deficiency, included,

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM HEPES buffer (pH 7.4) containing 100mM KCl, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Moro-Furlani., AM., et al. (1980) Ann. Hum. Genet. 43, 323-333;; Collet JF., et al. (1997) FEBS Lett. 408, 281-284 ;; Kim HY, et al. (2002) J Biol Chem. 277, 46651-8.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

25 kDa (225aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

MVSHSELRKL FYSADAVCFD VDSTVIREEG IDELAKICGV EDAVSEMTRR AMGGAVPFKA ALTERLALIQ PSREQVQRLI AEQPPHLTPG IRELVSRLQE RNVQVFLISG GFRSIVEHVA SKLNIPATNV FANRLKFYFN GEYAGFDETQ PTAESGGKGK VIKLLKEKFH FKKIIMIGDG ATDMEACPPA DAFIGFGGNV IRQQVKDNAK WYITDFVELL GELEE

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P78330

Internal Search Terms :

Phosphoserine phosphatase, PSPH, PSPH, Phosphoserine phosphatase Human, PSPase, PSP, EC 3.1.3.3, O-phosphoserine phosphohydrolase, L-3-phosphoserine phosphatase, Phosphoserine phosphatase, L 3 phosphoserine phosphatase, O phosphoserine phosphohydrolase, Phosphoserine phosphatase deficiency, included,PSP0501-10ug,PSP0501-20ug,PSP0501-50ug,PSP0501-100ug,PSP0501-250ug,PSP0501-500ug,PSP0501-1mg,PSP0501-10,PSP0501-20,PSP0501-50,PSP0501-100,PSP0501-250,PSP0501-500,PSP0501-1

more info or order :

NKMAX product webpage