Recombinant human Prolactin protein | NKMAX PRO0501 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Prolactin protein

catalog :

PRO0501

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Prolactin protein

Domain :

29-227aa

Catalog number (SKU) :

PRO0501

NCBI :

NP_000939.1

Description :

Prolactin is a hormone synthesised and secreted by lactotrope cells in the adenohypophysis (anterior pituitary gland). Prolactin has many effects, the most significant of which is to stimulate the mammary glands to produce milk (lactation). Increased serum prolactin during pregnancy causes enlargement of the mammary glands of the breasts and increases the production of milk. Recently, prolactin has demonstrated broader roles in breast cancer development, regulation of reproductive function, and immunoregulation. Prolactin was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

Alternative Names :

PRL, Prolactin, Lactogenic hormone, Luteotropic hormone, Mammotropin, OTTHuMP00000017727, Prolactin precursor.

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4)

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ben-jonathan N., et al. (1996) Endocr Rev. 17(6):639-69.;; Cooke NE., et al. (1981) J. Biol. Chem. 256, 4007-4016.;; Goffin V., et al. (1999) Mol Cell Endocrinol. 151, 79-87.;;

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range ≤ 0.5ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

23 kDa (200aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human Prolactin in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range ≤ 0.5ng/ml.

Amino Acid Sequence :

MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P01236

Internal Search Terms :

Prolactin, PRL, Prolactin, Lactogenic hormone, Luteotropic hormone, Mammotropin, OTTHuMP00000017727, Prolactin precursor.,PRO0501-10ug,PRO0501-20ug,PRO0501-50ug,PRO0501-100ug,PRO0501-250ug,PRO0501-500ug,PRO0501-1mg,PRO0501-10,PRO0501-20,PRO0501-50,PRO0501-100,PRO0501-250,PRO0501-500,PRO0501-1

more info or order :

NKMAX product webpage